Literature DB >> 10219816

The use and advantages of a multichannel vaginal cylinder in high-dose-rate brachytherapy.

D J Demanes1, S Rege, R R Rodriquez, K L Schutz, G A Altieri, T Wong.   

Abstract

PURPOSE: This paper describes California Endocurietherapy's (CET) high-dose-rate (HDR) multichannel cylinder, the rationale for its design, procedure for its insertion, and the dosimetry involved in its use. A study was done that compared the doses achieved using the CET multichannel cylinder to the same cylinder if it only had a central channel. METHODS AND MATERIALS: The CET multichannel vaginal cylinder was inexpensively constructed, using parts from various suppliers. After insertion in the patient, the cylinder is affixed to a base plate to prevent displacement. Two sets of orthogonal films (without and with rectal barium) are taken in preparation for digitization of the catheters, bladder, rectal, and pelvic sidewall points. Using HDR brachytherapy planning software, the dose distribution is adjusted to achieve the prescribed dose (5 Gy HDR) 5 mm lateral to the cylinder surface, 5 mm lateral at the proximal parametrial tissue, and 4 mm superior to the vaginal apex. Doses to the bladder and rectum are limited to approximately 85% and 75%, respectively, of the prescribed dose. The plan is optimized on geometric parameters. For dose comparison to treatment using a central channel cylinder, the lateral channels are de-activated, leaving only the central channel activated. Dose points are placed 5 mm laterally and superiorly from the cylinder surface, and the plan is optimized to deliver a uniform dose to the defined dose points. The doses and treatment volumes are statistically compared.
RESULTS: The CET multichannel cylinder allows much better dose control than the central channel cylinder. The multichannel cylinder achieves lower bladder and rectal doses by 14% and 15%, respectively, when compared to the central channel cylinder. By increasing the dwell times of certain dwell positions, the prescription dose is achieved in the vaginal apex and proximal parametrial tissues and along the length of the cylinder.
CONCLUSION: The multichannel cylinder enables more flexibility in isodose shaping and dose control to various points and structures when compared to the conventional central channel cylinder.

Entities:  

Mesh:

Year:  1999        PMID: 10219816     DOI: 10.1016/s0360-3016(98)00453-2

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  20 in total

1.  Treatment of pediatric vaginal rhabdomyosarcoma with the use of a real-time tracked custom applicator.

Authors:  Marc Morcos; Jennifer Vogel; Juan R Garcia; Veronica Gomez-Lobo; Steven Bartolac
Journal:  Brachytherapy       Date:  2022-03-18       Impact factor: 2.441

Review 2.  American Brachytherapy Task Group Report: Adjuvant vaginal brachytherapy for early-stage endometrial cancer: A comprehensive review.

Authors:  Matthew M Harkenrider; Alec M Block; Kaled M Alektiar; David K Gaffney; Ellen Jones; Ann Klopp; Akila N Viswanathan; William Small
Journal:  Brachytherapy       Date:  2016-05-31       Impact factor: 2.362

3.  Preliminary clinical outcomes of patients treated with vaginal brachytherapy alone using multi-channel vaginal brachytherapy applicator in operated early-stage endometrial cancer.

Authors:  Karthik S Rishi; Savitha David; Muddappa Pathikonda; Prakash Ramachandra; G V Giri; Annapurna Vadaparty; B S Srinath
Journal:  Rep Pract Oncol Radiother       Date:  2021-02-25

4.  Single versus multichannel applicator in high-dose-rate vaginal brachytherapy optimized by inverse treatment planning.

Authors:  Yasir A Bahadur; Camelia Constantinescu; Ashraf H Hassouna; Maha M Eltaher; Noor M Ghassal; Nesreen A Awad
Journal:  J Contemp Brachytherapy       Date:  2014-12-31

5.  A novel intracavitary applicator design for the treatment of deep vaginal fornices: preliminary dose metrics and geometric analysis.

Authors:  Antonio L Damato; Robert A Cormack; Akila N Viswanathan
Journal:  J Contemp Brachytherapy       Date:  2015-02-13

Review 6.  Brachytherapy for malignancies of the vagina in the 3D era.

Authors:  Scott M Glaser; Sushil Beriwal
Journal:  J Contemp Brachytherapy       Date:  2015-09-14

7.  A novel method for vaginal cylinder treatment planning: a seamless transition to 3D brachytherapy.

Authors:  Harish K Malhotra; Vincent Wu; Zhou Wang; Sachin Patil
Journal:  J Contemp Brachytherapy       Date:  2012-06-30

8.  Use of a Flexible Inflatable Multi-Channel Applicator for Vaginal Brachytherapy in the Management of Gynecologic Cancer.

Authors:  Samuel M Shin; Tamara L Duckworth; Benjamin T Cooper; John P Curtin; Peter B Schiff; J Keith DeWyngaert; Stella C Lymberis
Journal:  Front Oncol       Date:  2015-09-14       Impact factor: 6.244

9.  Feasibility study and optimum loading pattern of a multi-ring inflatable intravaginal applicator.

Authors:  Hsiang-Chi Kuo; Keyur J Mehta; Ravindra Yaparpalvi; Linda Hong; Dinesh Mynampati; Wolfgang A Tomé; Shalom Kalnicki
Journal:  J Contemp Brachytherapy       Date:  2013-06-28

10.  Comparison of doses to the rectum derived from treatment planning system with in-vivo dose values in vaginal vault brachytherapy using cylinder applicators.

Authors:  Emmanuel Oyeyemi Oyekunle; Rachel Ibhade Obed; Bidemi Idayat Akinlade; Atara Ntekim
Journal:  J Contemp Brachytherapy       Date:  2015-12-30
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