Literature DB >> 10209112

Transfer RNA biogenesis: A visa to leave the nucleus.

G Simos1, E Hurt.   

Abstract

Only correctly folded and mature tRNAs can leave the nucleus and enter the cytoplasm. Surprisingly, tRNA-aminoacylation has been found to occur, not only in the cytosol, but also inside the nucleus, where it may act as an additional proofreading step and facilitate the export of 'ready-to-function' aminoacyl-tRNAs.

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Year:  1999        PMID： 10209112     DOI： 10.1016/s0960-9822(99)80152-3

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  14 in total

1.  The intracellular location of two aminoacyl-tRNA synthetases depends on complex formation with Arc1p.

Authors:  K Galani; H Grosshans; K Deinert; E C Hurt; G Simos
Journal:  EMBO J       Date:  2001-12-03       Impact factor: 11.598

Review 2.  Transport into and out of the nucleus.

Authors:  I G Macara
Journal:  Microbiol Mol Biol Rev       Date:  2001-12       Impact factor: 11.056

3.  Significantly higher activity of a cytoplasmic hammerhead ribozyme than a corresponding nuclear counterpart: engineered tRNAs with an extended 3' end can be exported efficiently and specifically to the cytoplasm in mammalian cells.

Authors:  T Kuwabara; M Warashina; S Koseki; M Sano; J Ohkawa; K Nakayama; K Taira
Journal:  Nucleic Acids Res       Date:  2001-07-01       Impact factor: 16.971

4.  Polyadenylation of rRNA- and tRNA-based yeast transcripts cleaved by internal ribozyme activity.

Authors:  Katrin Düvel; Ralph Pries; Gerhard H Braus
Journal:  Curr Genet       Date:  2003-05-14       Impact factor: 3.886

Review 5.  Evolutionary conservation and expression of human RNA-binding proteins and their role in human genetic disease.

Authors:  Stefanie Gerstberger; Markus Hafner; Manuel Ascano; Thomas Tuschl
Journal:  Adv Exp Med Biol       Date:  2014       Impact factor: 2.622

6.  Replacement of the yeast TRP4 3' untranslated region by a hammerhead ribozyme results in a stable and efficiently exported mRNA that lacks a poly(A) tail.

Authors:  Katrin Düvel; Oliver Valerius; David A Mangus; Allan Jacobson; Gerhard H Braus
Journal:  RNA       Date:  2002-03       Impact factor: 4.942

7.  Nuclear tRNA aminoacylation and its role in nuclear export of endogenous tRNAs in Saccharomyces cerevisiae.

Authors:  S Sarkar; A K Azad; A K Hopper
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-07       Impact factor: 11.205

8.  Identification of tRNA-derived ncRNAs in TCGA and NCI-60 panel cell lines and development of the public database tRFexplorer.

Authors:  Alessandro La Ferlita; Salvatore Alaimo; Dario Veneziano; Giovanni Nigita; Veronica Balatti; Carlo M Croce; Alfredo Ferro; Alfredo Pulvirenti
Journal:  Database (Oxford)       Date:  2019-01-01       Impact factor: 3.451

9.  An aminoacylation-dependent nuclear tRNA export pathway in yeast.

Authors:  H Grosshans; E Hurt; G Simos
Journal:  Genes Dev       Date:  2000-04-01       Impact factor: 11.361

Review 10.  Transfer RNA post-transcriptional processing, turnover, and subcellular dynamics in the yeast Saccharomyces cerevisiae.

Authors:  Anita K Hopper
Journal:  Genetics       Date:  2013-05       Impact factor: 4.562
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