Literature DB >> 10192923

Methylation of tea catechins by rat liver homogenates.

K Okushio1, M Suzuki, N Matsumoto, F Nanjo, Y Hara.   

Abstract

Methylation of (-)-epigallocatechin (EGC), (-)-epicatechin gallate (ECg), and (-)-epigallocatechin gallate (EGCg) was carried out with a rat liver homogenate and S-adenosyl-L-methionine. A structural analysis of the reaction products by MS and NMR showed that 4'-O-methyl EGC, 4"-O-methyl ECg, and 4"-O-methyl EGCg had been formed from EGC, ECg, and EGCg, respectively. These results suggest that methylation may be one of the metabolic pathways to the catechins.

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Year:  1999        PMID： 10192923     DOI： 10.1271/bbb.63.430

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  9 in total

1.  Inhibition of catechol-Omicron-methyltransferase activity in human breast cancer cells enhances the biological effect of the green tea polyphenol (-)-EGCG.

Authors:  Kristin Landis-Piwowar; Di Chen; Tak Hang Chan; Q Ping Dou
Journal:  Oncol Rep       Date:  2010-08       Impact factor: 3.906

2.  High-dose green tea polyphenols induce nephrotoxicity in dextran sulfate sodium-induced colitis mice by down-regulation of antioxidant enzymes and heat-shock protein expressions.

Authors:  Hirofumi Inoue; Satoko Akiyama; Mari Maeda-Yamamoto; Atsushi Nesumi; Takuji Tanaka; Akira Murakami
Journal:  Cell Stress Chaperones       Date:  2011-07-16       Impact factor: 3.667

Review 3.  Green tea polyphenols as proteasome inhibitors: implication in chemoprevention.

Authors:  H Yang; K Landis-Piwowar; T H Chan; Q P Dou
Journal:  Curr Cancer Drug Targets       Date:  2011-03       Impact factor: 3.428

4.  Antitumor activity of novel fluoro-substituted (-)-epigallocatechin-3-gallate analogs.

Authors:  Huanjie Yang; Dong Kui Sun; Di Chen; Qiuzhi Cindy Cui; Yan Yan Gu; Tao Jiang; Wei Chen; Sheng Biao Wan; Q Ping Dou
Journal:  Cancer Lett       Date:  2009-12-03       Impact factor: 8.679

5.  Beneficial effects of green tea: a literature review.

Authors:  Sabu M Chacko; Priya T Thambi; Ramadasan Kuttan; Ikuo Nishigaki
Journal:  Chin Med       Date:  2010-04-06       Impact factor: 5.455

Review 6.  Natural compounds with proteasome inhibitory activity for cancer prevention and treatment.

Authors:  H Yang; K R Landis-Piwowar; D Chen; V Milacic; Q P Dou
Journal:  Curr Protein Pept Sci       Date:  2008-06       Impact factor: 3.272

7.  Proteasome inhibition in human breast cancer cells with high catechol-O-methyltransferase activity by green tea polyphenol EGCG analogs.

Authors:  Congde Huo; Huanjie Yang; Qiuzhi Cindy Cui; Q Ping Dou; Tak Hang Chan
Journal:  Bioorg Med Chem       Date:  2009-12-16       Impact factor: 3.641

8.  A para-amino substituent on the D-ring of green tea polyphenol epigallocatechin-3-gallate as a novel proteasome inhibitor and cancer cell apoptosis inducer.

Authors:  Kumi Osanai; Kristin R Landis-Piwowar; Q Ping Dou; Tak Hang Chan
Journal:  Bioorg Med Chem       Date:  2007-05-18       Impact factor: 3.641

Review 9.  Prooxidant Effects of Epigallocatechin-3-Gallate in Health Benefits and Potential Adverse Effect.

Authors:  Jie Ouyang; Kun Zhu; Zhonghua Liu; Jianan Huang
Journal:  Oxid Med Cell Longev       Date:  2020-08-12       Impact factor: 6.543
  9 in total

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