Literature DB >> 20045338

Proteasome inhibition in human breast cancer cells with high catechol-O-methyltransferase activity by green tea polyphenol EGCG analogs.

Congde Huo1, Huanjie Yang, Qiuzhi Cindy Cui, Q Ping Dou, Tak Hang Chan.   

Abstract

A pro-drug 8 of a synthetic analog 7 is more active in its antiproliferative activity against human breast cancer MDA-MB-231 cells possessing high catechol-O-methyltransferase (COMT) activity than the pro-drugs of EGCG and the analog 5. The higher activity of 8 is attributed to it not being a substrate of COMT. Copyright (c) 2009 Elsevier Ltd. All rights reserved.

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Year:  2009        PMID： 20045338      PMCID： PMC2819655          DOI： 10.1016/j.bmc.2009.12.034

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  32 in total

Review 1.  Ubiquitin-mediated proteolysis: biological regulation via destruction.

Authors:  A Ciechanover; A Orian; A L Schwartz
Journal:  Bioessays       Date:  2000-05       Impact factor: 4.345

Review 2.  Methylation pharmacogenetics: catechol O-methyltransferase, thiopurine methyltransferase, and histamine N-methyltransferase.

Authors:  R M Weinshilboum; D M Otterness; C L Szumlanski
Journal:  Annu Rev Pharmacol Toxicol       Date:  1999       Impact factor: 13.820

3.  Enzymology of methylation of tea catechins and inhibition of catechol-O-methyltransferase by (-)-epigallocatechin gallate.

Authors:  Hong Lu; Xiaofeng Meng; Chung S Yang
Journal:  Drug Metab Dispos       Date:  2003-05       Impact factor: 3.922

4.  Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts.

Authors:  B An; R H Goldfarb; R Siman; Q P Dou
Journal:  Cell Death Differ       Date:  1998-12       Impact factor: 15.828

Review 5.  Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors.

Authors:  P T Männistö; S Kaakkola
Journal:  Pharmacol Rev       Date:  1999-12       Impact factor: 25.468

6.  Peracetylation as a means of enhancing in vitro bioactivity and bioavailability of epigallocatechin-3-gallate.

Authors:  Joshua D Lambert; Shengmin Sang; Jungil Hong; Seok-Joo Kwon; Mao-Jung Lee; Chi-Tang Ho; Chung S Yang
Journal:  Drug Metab Dispos       Date:  2006-09-22       Impact factor: 3.922

7.  Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia: a preliminary report from a one-year proof-of-principle study.

Authors:  Saverio Bettuzzi; Maurizio Brausi; Federica Rizzi; Giovanni Castagnetti; Giancarlo Peracchia; Arnaldo Corti
Journal:  Cancer Res       Date:  2006-01-15       Impact factor: 12.701

8.  Evaluation of proteasome-inhibitory and apoptosis-inducing potencies of novel (-)-EGCG analogs and their prodrugs.

Authors:  Kristin R Landis-Piwowar; Deborah J Kuhn; Sheng Biao Wan; Di Chen; Tak Hang Chan; Q Ping Dou
Journal:  Int J Mol Med       Date:  2005-04       Impact factor: 4.101

9.  A potential prodrug for a green tea polyphenol proteasome inhibitor: evaluation of the peracetate ester of (-)-epigallocatechin gallate [(-)-EGCG].

Authors:  Wai Har Lam; Aslamuzzaman Kazi; Deborah J Kuhn; Larry M C Chow; Albert S C Chan; Q Ping Dou; Tak Hang Chan
Journal:  Bioorg Med Chem       Date:  2004-11-01       Impact factor: 3.641

Review 10.  Tea polyphenols, their biological effects and potential molecular targets.

Authors:  D Chen; V Milacic; M S Chen; S B Wan; W H Lam; C Huo; K R Landis-Piwowar; Q C Cui; A Wali; T H Chan; Q P Dou
Journal:  Histol Histopathol       Date:  2008-04       Impact factor: 2.303
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  15 in total

Review 1.  Targeting tumor ubiquitin-proteasome pathway with polyphenols for chemosensitization.

Authors:  Min Shen; Tak Hang Chan; Q Ping Dou
Journal:  Anticancer Agents Med Chem       Date:  2012-10-01       Impact factor: 2.505

2.  Computational modeling of the potential interactions of the proteasome beta5 subunit and catechol-O-methyltransferase-resistant EGCG analogs.

Authors:  Jyoti Kanwar; Imthiyaz Mohammad; Huanjie Yang; Congde Huo; Tak Hang Chan; Q Ping Dou
Journal:  Int J Mol Med       Date:  2010-08       Impact factor: 4.101

3.  A preliminary investigation of the impact of catechol-O-methyltransferase genotype on the absorption and metabolism of green tea catechins.

Authors:  Rosalind J Miller; Kim G Jackson; Tony Dadd; Beate Nicol; Joanne L Dick; Andrew E Mayes; A Louise Brown; Anne M Minihane
Journal:  Eur J Nutr       Date:  2011-03-29       Impact factor: 5.614

4.  Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells.

Authors:  Di Chen; Sreedhar Pamu; Qiuzhi Cui; Tak Hang Chan; Q Ping Dou
Journal:  Bioorg Med Chem       Date:  2012-03-09       Impact factor: 3.641

5.  Targeting the ubiquitin-proteasome system for cancer treatment: discovering novel inhibitors from nature and drug repurposing.

Authors:  Claire L Soave; Tracey Guerin; Jinbao Liu; Q Ping Dou
Journal:  Cancer Metastasis Rev       Date:  2017-12       Impact factor: 9.264

6.  The modulatory effect of polyphenols from green tea, oolong tea and black tea on human intestinal microbiota in vitro.

Authors:  Hanyang Sun; Yuhui Chen; Mei Cheng; Xin Zhang; Xiaojie Zheng; Zhicheng Zhang
Journal:  J Food Sci Technol       Date:  2017-12-02       Impact factor: 2.701

7.  Effect of particle size on the bioaccessibility of polyphenols and polysaccharides in green tea powder and its antioxidant activity after simulated human digestion.

Authors:  Yang Shu; Jie Li; Xiaoping Yang; Xinyang Dong; Xujie Wang
Journal:  J Food Sci Technol       Date:  2019-01-22       Impact factor: 2.701

Review 8.  Green tea polyphenols as proteasome inhibitors: implication in chemoprevention.

Authors:  H Yang; K Landis-Piwowar; T H Chan; Q P Dou
Journal:  Curr Cancer Drug Targets       Date:  2011-03       Impact factor: 3.428

Review 9.  Recent advances on tea polyphenols.

Authors:  Jyoti Kanwar; Mujtaba Taskeen; Imthiyaz Mohammad; Congde Huo; Tak Hang Chan; Qing Ping Dou
Journal:  Front Biosci (Elite Ed)       Date:  2012-01-01

10.  Epigenetic targets of bioactive dietary components for cancer prevention and therapy.

Authors:  Syed M Meeran; Amiya Ahmed; Trygve O Tollefsbol
Journal:  Clin Epigenetics       Date:  2010-12-01       Impact factor: 6.551
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