Literature DB >> 1017593

Serum glycoproteins in the liver diseases. II. Radioimmunoassay of alpha-1 acid glycoprotein.

T Arima, Y Motoyama, K Nagata, T Kondo.   

Abstract

A radioimmunoassay for human alpha1-acid glycoprotein has been developed. 97.8% of 125I-alpha1-acid glycoprotein prepared for the assay were immunoprecipitable with specific anti-sera against the protein. alpha1-acid glycoprotein concentration in sera from normal adults was found to range between 70 and 114 mg/100 ml, with a mean of 93. Fulminant hepatitis, liver cirrhosis or chronic active hepatitis with sublobular necrosis caused a significant lowering of alpha1-acid glycoprotein concentration. Sera obtained from patients with acute hepatitis in convalescence, chronic inactive hepatitis or primary biliary cirrhosis gave normal concentration of the glycoprotein.

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Year:  1976        PMID： 1017593

Source DB:  PubMed          Journal:  Gastroenterol Jpn        ISSN： 0435-1339


  22 in total

1.  BIOCHEMICAL SIGNIFICANCE OF SERUM GLYCOPROTEINS. 3. HEPATIC PRODUCTION OF A1 AND A2 GLOBULINS RESPONDING TO INJURY.

Authors:  O W NEUHAUS; A LIU
Journal:  Proc Soc Exp Biol Med       Date:  1964-10

2.  A quantitative abnormality in serum mucoproteins in the Marfan syndrome.

Authors:  H BACCHUS
Journal:  Am J Med       Date:  1958-11       Impact factor: 4.965

3.  Content and composition of the mucoprotein fraction of human serum (seromucoid) in disease with special reference to hematologic disorders.

Authors:  E MOSCHIDES; M STEFANINI; S I MAGALINI; S A KISTNER
Journal:  J Clin Invest       Date:  1958-01       Impact factor: 14.808

4.  Studies of serum mucoprotein (seromucoid). I. A turbidimetric method.

Authors:  J DE LA HUERGA; A DUBIN; D S KUSHNER; H A DYNIEWICZ; H POPPER
Journal:  J Lab Clin Med       Date:  1956-03

5.  A comparative study of the serum glycoproteins in patients with parenchymatous hepatic disease or metastatic neoplasia.

Authors:  E M GREENSPAN; I LEHMAN; M M GRAFF; E B SCHOENBACH
Journal:  Cancer       Date:  1951-09       Impact factor: 6.860

6.  Serum mucoprotein and guanase levels in the differential diagnosis of jaundice.

Authors:  F Steigmann; V C Gandhi; D Silverman; A Dubin
Journal:  Am J Gastroenterol       Date:  1971-08       Impact factor: 10.864

7.  Immunochemical quantitation of antigens by single radial immunodiffusion.

Authors:  G Mancini; A O Carbonara; J F Heremans
Journal:  Immunochemistry       Date:  1965-09

8.  Serum alpha 1-acid glycoprotein in chronic ulcerative colitis.

Authors:  W H Dearing; W F McGuckin; L R Elveback
Journal:  Gastroenterology       Date:  1969-02       Impact factor: 22.682

9.  Serum seromucoid and acid mucopolysaccharide in the Marfan syndrome.

Authors:  H BACCHUS
Journal:  J Lab Clin Med       Date:  1960-02

10.  Orosomucoid content of pleural and peritoneal effusions.

Authors:  D Rudman; R K Chawla; A E Del Rio; B M Hollins; E C Hall; J M Conn
Journal:  J Clin Invest       Date:  1974-07       Impact factor: 14.808
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  2 in total

1.  Serum glycoproteins in the liver diseases. IV. Alpha-1 acid glycoprotein level in liver cirrhosis.

Authors:  T Arima; Y Motoyama; T Yamamoto; K Nagata; T Kondo
Journal:  Gastroenterol Jpn       Date:  1977

2.  A radioimmunoassay for quantitation of secretory component.

Authors:  K Kunishi
Journal:  Gastroenterol Jpn       Date:  1980-04
  2 in total

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