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Literature DB >> 892335

Serum glycoproteins in the liver diseases. IV. Alpha-1 acid glycoprotein level in liver cirrhosis.

T Arima, Y Motoyama, T Yamamoto, K Nagata, T Kondo.

Abstract

Circulating alpha-1 acid glycoprotein level in cirrhotic patients was determined by radioimmunoassay, and was compared to the ones in normal subjects and chronic active hepatitis with sublobular necrosis. Serum alpha-1 acid glycoprotein levels in liver cirrhosis (p less than 0.001) and chronic active hepatitis with sublobular necrosis (p less than 0.02) were significantly reduced comparing to the normal subjects, although any statistically significant difference was not observed between the formers. In liver cirrhosis, thie serum alpha-1 acid glycoprotein level correlated negatively with serum albumin concentration but neither with serum alpha-1 globulin fraction nor with Indocyanine green clearance rate.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 1977 PMID： 892335 DOI： 10.1007/bf02773624

Source DB: PubMed Journal: Gastroenterol Jpn ISSN： 0435-1339

9 in total

1. Survey of clinical significance of serum mucoprotein level.

Authors: E M GREENSPAN
Journal: AMA Arch Intern Med Date: 1954-06

Review 2. The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins.

Authors: G Ashwell; A G Morell
Journal: Adv Enzymol Relat Areas Mol Biol Date: 1974

Review 3. On the biological role of glycoproteins.

Authors: E H Eylar
Journal: J Theor Biol Date: 1966-01 Impact factor: 2.691

4. The metabolism of plasma glycoproteins. I. Studies on the rate of incorporation of glucosamine-1-14C into protein-bound hexosamine and N-acetylneuraminic acid in the normal rat.

Authors: R A Macbeth; J G Bekesi; E Sugden; S Bice
Journal: J Biol Chem Date: 1965-10 Impact factor: 5.157

2 in total

1. Ricinus communis agglutinin II-reactive glycoproteins from the ascites of patients with hepatocellular carcinoma and their use in enzyme-linked immunosorbent assay.

Authors: M Fukushima; T Arima; H Nagashima
Journal: Gastroenterol Jpn Date: 1987-04

2. Serum glycoproteins in the liver diseases. VIII. Desialylated glycoproteins in the liver cirrhosis.

Authors: T Arima
Journal: Gastroenterol Jpn Date: 1979-08

2 in total

Serum glycoproteins in the liver diseases. IV. Alpha-1 acid glycoprotein level in liver cirrhosis.

1. Survey of clinical significance of serum mucoprotein level.

Review 2. The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins.

Review 3. On the biological role of glycoproteins.

4. The metabolism of plasma glycoproteins. I. Studies on the rate of incorporation of glucosamine-1-14C into protein-bound hexosamine and N-acetylneuraminic acid in the normal rat.

5. Serum glycoproteins in the liver diseases. II. Radioimmunoassay of alpha-1 acid glycoprotein.

6. Measurement of circulating desialylated glycoproteins and correlation with hepatocellular damage.

7. Albumin synthesis in cirrhotic subjects with ascites studied with carbonate-14C.

8. Orosomucoid content of pleural and peritoneal effusions.

9. Studies on the mucoproteins of human plasma; plasma mucoprotein levels in cancer patients.

1. Ricinus communis agglutinin II-reactive glycoproteins from the ascites of patients with hepatocellular carcinoma and their use in enzyme-linked immunosorbent assay.

2. Serum glycoproteins in the liver diseases. VIII. Desialylated glycoproteins in the liver cirrhosis.