Literature DB >> 10147281

The characterisation of inhalation devices by an inhalation simulator: The Electronic Lung.

A Brindley1, B S Sumby, I J Smith.   

Abstract

The Electronic Lung is an inhalation simulator designed for the characterisation of breath-actuated inhalation devices. It enables the in-vitro evaluation of devices under conditions that have been produced in-vivo. Data generated on the Serevent Diskhaler inhaler have highlighted the reproducibility of particle size distribution of drug delivered from the device over a range of inhalation parameters.

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Year:  1994        PMID: 10147281     DOI: 10.1089/jam.1994.7.197

Source DB:  PubMed          Journal:  J Aerosol Med        ISSN: 0894-2684


  3 in total

1.  Influence of realistic inspiratory flow profiles on fine particle fractions of dry powder aerosol formulations.

Authors:  Gary P Martin; Christopher Marriott; Xian-Ming Zeng
Journal:  Pharm Res       Date:  2006-12-20       Impact factor: 4.200

2.  Developing ways to evaluate in the laboratory how inhalation devices will be used by patients and care-givers: the need for clinically appropriate testing.

Authors:  Jolyon P Mitchell; Jason A Suggett
Journal:  AAPS PharmSciTech       Date:  2014-06-04       Impact factor: 3.246

3.  In Vitro Dosing Performance of the ELLIPTA® Dry Powder Inhaler Using Asthma and COPD Patient Inhalation Profiles Replicated with the Electronic Lung (eLung™).

Authors:  Melanie Hamilton; Richard Leggett; Cheng Pang; Stephen Charles; Ben Gillett; David Prime
Journal:  J Aerosol Med Pulm Drug Deliv       Date:  2015-09-15       Impact factor: 2.849

  3 in total

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