Literature DB >> 1009688

Adenosine deaminase activity in thymus and other human tissues.

A Adams, R A Harkness.   

Abstract

Adenosine deaminase activity (ADA) has been estimated in human tissues. Levels in the thymus during childhood were very much higher than in any of the other 6 tissues studied. Intermediate activities were obtained from spleen and lymph nodes and also skin. Cerebral cortex, liver and kidney had relatively low levels. ADA activity in lymphocytes from peripheral blood was significantly increased after antigenic stimulation by TAB immunization. The available evidence appears to be consistent with T-lymphocyte growth and development in the thymus being dependant on ADA.

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Year:  1976        PMID： 1009688      PMCID： PMC1540957     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  11 in total

1.  A STUDY OF THE TISSUE DISTRIBUTION OF ADENOSINE DEAMINASE IN SIX MAMMAL SPECIES.

Authors:  T G BRADY; C I O'DONOVAN
Journal:  Comp Biochem Physiol       Date:  1965-01

2.  Adenosine deaminase activity in lymphoid cells during antibody production.

Authors:  J G HALL
Journal:  Aust J Exp Biol Med Sci       Date:  1963-02

3.  Studies of the enzymes of purine metabolism in skin. II. Nucleoside deaminases of rat skin.

Authors:  W D BLOCK; D V JOHNSON
Journal:  J Invest Dermatol       Date:  1954-12       Impact factor: 8.551

4.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

5.  Nucleoside deaminase and adenosine deaminase activities in regenerating mouse liver.

Authors:  I K Rothman; R Silber; K M Klein; F F Becker
Journal:  Biochim Biophys Acta       Date:  1971-01-28

6.  Evaluation of adenosine deaminase and other purine salvage pathway enzymes in horses with combined immunodeficiency.

Authors:  T C McGuire; B Pollara; J J Moore; M J Poppie
Journal:  Infect Immun       Date:  1976-03       Impact factor: 3.441

7.  Effect of adenosine deaminase inhibition upon human lymphocyte blastogenesis.

Authors:  D A Carson; J E Seegmiller
Journal:  J Clin Invest       Date:  1976-02       Impact factor: 14.808

8.  Adenosine deaminase activity in chronic lymphocytic leukemia. Relationship to B- and T-cell subpopulations.

Authors:  R Tung; R Silber; F Quagliata; M Conklyn; J Gottesman; R Hirschhorn
Journal:  J Clin Invest       Date:  1976-03       Impact factor: 14.808

9.  Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity.

Authors:  E R Giblett; A J Ammann; D W Wara; R Sandman; L K Diamond
Journal:  Lancet       Date:  1975-05-03       Impact factor: 79.321

10.  Role of adenosine deaminase in lymphocyte proliferation.

Authors:  T Hovi; J F Smyth; A C Allison; S C Williams
Journal:  Clin Exp Immunol       Date:  1976-03       Impact factor: 4.330
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  27 in total

1.  Adenosine deaminase activity in erythrocytes, lymphocytes, polymorphonuclear neutrophil leucocytes and cultured cells: a possible role in the immune response.

Authors:  A Adams; R A Harkness; J G McVie
Journal:  J Inherit Metab Dis       Date:  1978       Impact factor: 4.982

2.  Elevated adenosine deaminase levels in celiac disease.

Authors:  Basak Cakal; Yavuz Beyazit; Seyfettin Koklu; Erdem Akbal; Ibrahim Biyikoglu; Gulsen Yilmaz
Journal:  J Clin Lab Anal       Date:  2010       Impact factor: 2.352

3.  Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: possible role of nucleoside kinase(s).

Authors:  D A Carson; J Kaye; J E Seegmiller
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

Review 4.  Heberden oration 1979: human aberrations of purine metabolism and their significance for rheumatology.

Authors:  J E Seegmiller
Journal:  Ann Rheum Dis       Date:  1980-04       Impact factor: 19.103

Review 5.  Antineoplastic drugs in 1990. A review (Part II).

Authors:  D J Black; R B Livingston
Journal:  Drugs       Date:  1990-05       Impact factor: 9.546

6.  Comparative genomic and expression analysis of the adenosine signaling pathway members in Xenopus.

Authors:  Alice Tocco; Benoît Pinson; Pierre Thiébaud; Nadine Thézé; Karine Massé
Journal:  Purinergic Signal       Date:  2014-10-16       Impact factor: 3.765

Review 7.  Clinical biochemistry of the neonatal period: immaturity, hypoxia, and metabolic disease.

Authors:  R A Harkness
Journal:  J Clin Pathol       Date:  1987-09       Impact factor: 3.411

8.  Biochemical basis for the enhanced toxicity of deoxyribonucleosides toward malignant human T cell lines.

Authors:  D A Carson; J Kaye; S Matsumoto; J E Seegmiller; L Thompson
Journal:  Proc Natl Acad Sci U S A       Date:  1979-05       Impact factor: 11.205

9.  In vitro of adenosine on lymphocytes and erythrocytes from horses with combined immunodeficiency.

Authors:  N S Magnuson; L E Perryman
Journal:  J Clin Invest       Date:  1979-07       Impact factor: 14.808

10.  Coordinate regulation of mRNAs encoding adenosine deaminase, purine nucleoside phosphorylase, and terminal deoxynucleotidyltransferase by phorbol esters in human thymocytes.

Authors:  H Martinez-Valdez; A Cohen
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205
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