Literature DB >> 10080100

Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1).

G Fantuzzi1, C A Dinarello.   

Abstract

This special article deals with the role of processing enzymes in the generation of bioactive cytokines, particularly IL-1 beta and the novel cytokine IL-18, which was formerly called IFN gamma-inducing factor (IGIF). The "classical" pathways of cytokine processing are described, as well as the importance of alternative cleavage enzymes. The topic of this review also concerns the biology of IL-18. The regulation of IL-18 production, the IL-18 receptor complex, and the biological effects of this novel cytokine are described.

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Year:  1999        PMID： 10080100     DOI： 10.1023/a:1020506300324

Source DB:  PubMed          Journal:  J Clin Immunol        ISSN： 0271-9142            Impact factor:   8.542


  112 in total

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Journal:  Nature       Date:  1997-02-20       Impact factor: 49.962

2.  A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells.

Authors:  R A Black; C T Rauch; C J Kozlosky; J J Peschon; J L Slack; M F Wolfson; B J Castner; K L Stocking; P Reddy; S Srinivasan; N Nelson; N Boiani; K A Schooley; M Gerhart; R Davis; J N Fitzner; R S Johnson; R J Paxton; C J March; D P Cerretti
Journal:  Nature       Date:  1997-02-20       Impact factor: 49.962

3.  A matrix metalloproteinase inhibitor prevents processing of tumor necrosis factor alpha (TNF alpha) and abrogates endotoxin-induced lethality.

Authors:  C C Solorzano; R Ksontini; J H Pruitt; T Auffenberg; C Tannahill; R E Galardy; G P Schultz; S L MacKay; E M Copeland; L L Moldawer
Journal:  Shock       Date:  1997-06       Impact factor: 3.454

4.  Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme.

Authors:  Y Gu; K Kuida; H Tsutsui; G Ku; K Hsiao; M A Fleming; N Hayashi; K Higashino; H Okamura; K Nakanishi; M Kurimoto; T Tanimoto; R A Flavell; V Sato; M W Harding; D J Livingston; M S Su
Journal:  Science       Date:  1997-01-10       Impact factor: 47.728

5.  Defective NK cell activity and Th1 response in IL-18-deficient mice.

Authors:  K Takeda; H Tsutsui; T Yoshimoto; O Adachi; N Yoshida; T Kishimoto; H Okamura; K Nakanishi; S Akira
Journal:  Immunity       Date:  1998-03       Impact factor: 31.745

6.  Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer.

Authors:  N P Walker; R V Talanian; K D Brady; L C Dang; N J Bump; C R Ferenz; S Franklin; T Ghayur; M C Hackett; L D Hammill
Journal:  Cell       Date:  1994-07-29       Impact factor: 41.582

7.  Interleukin-8 processing by neutrophil elastase, cathepsin G and proteinase-3.

Authors:  M Padrines; M Wolf; A Walz; M Baggiolini
Journal:  FEBS Lett       Date:  1994-09-26       Impact factor: 4.124

8.  Purification and characterization of a unique human interleukin 1 from the tumor cell line U937.

Authors:  P J Knudsen; C A Dinarello; T B Strom
Journal:  J Immunol       Date:  1986-05-01       Impact factor: 5.422

9.  Structure-activity relationships of interleukin-8 determined using chemically synthesized analogs. Critical role of NH2-terminal residues and evidence for uncoupling of neutrophil chemotaxis, exocytosis, and receptor binding activities.

Authors:  I Clark-Lewis; C Schumacher; M Baggiolini; B Moser
Journal:  J Biol Chem       Date:  1991-12-05       Impact factor: 5.157

Review 10.  The inflammatory response in interleukin-1 beta-deficient mice: comparison with other cytokine-related knock-out mice.

Authors:  G Fantuzzi; C A Dinarello
Journal:  J Leukoc Biol       Date:  1996-04       Impact factor: 4.962
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  147 in total

1.  Plasma levels of interleukin-18 and interleukin-18 binding protein are elevated in patients with chronic liver disease.

Authors:  Othmar Ludwiczek; Arthur Kaser; Daniela Novick; Charles A Dinarello; Menachem Rubinstein; Wolfgang Vogel; Herbert Tilg
Journal:  J Clin Immunol       Date:  2002-11       Impact factor: 8.317

Review 2.  Regulating caspase-1 during infection: roles of NLRs, AIM2, and ASC.

Authors:  Christopher L Case
Journal:  Yale J Biol Med       Date:  2011-12

Review 3.  The cooperation between the autophagy machinery and the inflammasome to implement an appropriate innate immune response: do they regulate each other?

Authors:  Dalia H A Abdelaziz; Hany Khalil; Estelle Cormet-Boyaka; Amal O Amer
Journal:  Immunol Rev       Date:  2015-05       Impact factor: 12.988

Review 4.  IL-1 pathways in inflammation and human diseases.

Authors:  Cem Gabay; Céline Lamacchia; Gaby Palmer
Journal:  Nat Rev Rheumatol       Date:  2010-02-23       Impact factor: 20.543

5.  Interdisciplinary collaborative team for blastocyst implantation research: inception and perspectives.

Authors:  Koji Yoshinaga; Mercy PrabhuDas; Christopher Davies; Kenneth White; Kathleen Caron; Thaddeus Golos; Asgerally Fazleabas; Bibhash Paria; Gil Mor; Soumen Paul; Xiaoqin Ye; Sudhansu K Dey; Thomas Spencer; Robert Michael Roberts
Journal:  Am J Reprod Immunol       Date:  2013-11-29       Impact factor: 3.886

6.  Asc and Ipaf Inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila.

Authors:  Christopher L Case; Sunny Shin; Craig R Roy
Journal:  Infect Immun       Date:  2009-02-23       Impact factor: 3.441

7.  IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation.

Authors:  B Siegmund; H A Lehr; G Fantuzzi; C A Dinarello
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-23       Impact factor: 11.205

Review 8.  Pyroptosis: host cell death and inflammation.

Authors:  Tessa Bergsbaken; Susan L Fink; Brad T Cookson
Journal:  Nat Rev Microbiol       Date:  2009-02       Impact factor: 60.633

9.  Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta.

Authors:  Leo A B Joosten; Mihai G Netea; Giamila Fantuzzi; Marije I Koenders; Monique M A Helsen; Helmut Sparrer; Christine T Pham; Jos W M van der Meer; Charles A Dinarello; Wim B van den Berg
Journal:  Arthritis Rheum       Date:  2009-12

10.  Selective deletion of CD8(+) cells upregulated by caspases-1 via IL-18 in mice immunized with major outer membrane protein of Shigella dysenteriae 1 following infection.

Authors:  Ashim Kumar Bagchi; Ajoy Kumar Sinha; Rushita Adhikari; Pradip Maiti; Joydeep Mukherjee; Arpita Panda; Dhira Rani Saha
Journal:  J Clin Immunol       Date:  2010-01-19       Impact factor: 8.317
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