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Literature DB >> 10036978

Molecular correlates of the murine Xce locus.

P Avner¹, M Prissette, D Arnaud, B Courtier, C Cecchi, E Heard.

Abstract

The murine Xce locus, first identified by Bruce Cattanach, influences the primary choice of the X chromosome to be inactivated. Methylation of a GC-rich region (DXPas34) that includes multiple 34 bp repeats and lies some 15 kb 3' to Xist has been shown to vary with Xce haplotype. The degree of methylation on the active X chromosome at this locus represents one of the few molecular correlates of Xce action currently available. Data relating to the specificity and other characteristics of this association are presented.

Entities: Gene Species

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Year: 1998 PMID： 10036978 DOI： 10.1017/s0016672398003516

Source DB: PubMed Journal: Genet Res ISSN： 0016-6723 Impact factor: 1.588

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Cited

9 in total

Molecular correlates of the murine Xce locus.

1. Functional analysis of the DXPas34 locus, a 3' regulator of Xist expression.

2. Antisense transcription through the Xist locus mediates Tsix function in embryonic stem cells.

Review 3. Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control.

4. Identification of developmentally specific enhancers for Tsix in the regulation of X chromosome inactivation.

5. Functional intergenic transcription: a case study of the X-inactivation centre.

6. An N-ethyl-N-nitrosourea mutagenesis screen for epigenetic mutations in the mouse.

7. A skewed view of X chromosome inactivation.

Review 8. Genomic imprinting mechanisms in mammals.

9. Intersection of the RNA interference and X-inactivation pathways.