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Literature DB >> 999515

Temperature-sensitive virion transcriptase activity in mutants of WSN influenza virus.

Abstract

Temperature-sensitive mutants of WSN influenza virus (10, 11, 12) were tested in vitro for activity of the virion RNA-dependent RNA transcriptase at various temperatures. Temperature-sensitivity was found for virion transcriptase activity of mutants belonging to complementation/recombination group I, but not groups II, IV and V. It was not possible on the basis of the results to specify the precise biochemical lesion of mutants from group III.

Entities: Disease

Mesh：

Substances：

Year: 1976 PMID： 999515 DOI： 10.1007/bf01317872

Source DB: PubMed Journal: Arch Virol ISSN： 0304-8608 Impact factor: 2.574

11 in total

1. Temperature-sensitive mutants of influenza WSN virus defective in virus-specific RNA synthesis.

Authors: R M Krug; M Ueda; P Palese
Journal: J Virol Date: 1975-10 Impact factor: 5.103

2. Further isolation and characterization of temperature-sensitive mutants of influenza virus.

Authors: A Sugiura; M Ueda; K Tobita; C Enomoto
Journal: Virology Date: 1975-06 Impact factor: 3.616

3. Influenza virion RNA-dependent RNA polymerase: stimulation by guanosine and related compounds.

Authors: D McGeoch; N Kitron
Journal: J Virol Date: 1975-04 Impact factor: 5.103

4. Characterization of temperature sensitive influenza virus mutants defective in neuraminidase.

Authors: P Palese; K Tobita; M Ueda; R W Compans
Journal: Virology Date: 1974-10 Impact factor: 3.616

5. Primary transcription of the influenza virus genome in permissive cells.

Authors: W J Bean; R W Simpson
Journal: Virology Date: 1973-12 Impact factor: 3.616

6. Isolation and preliminary characterization of temperature-sensitive mutants of influenza virus.

Authors: A Sugiura; K Tobita; E D Kilbourne
Journal: J Virol Date: 1972-10 Impact factor: 5.103

7. Temperature-sensitive mutants of influenza virus. Isolation and preliminary characterization.

Authors: M Ueda
Journal: Arch Gesamte Virusforsch Date: 1972

8. Transcription of the influenza ribonucleic acid genome by a virion polymerase. 3. Completeness of the transcription process.

Authors: D H Bishop; P Roy; W J Bean; R W Simpson
Journal: J Virol Date: 1972-10 Impact factor: 5.103

9. Virion-associated transcriptase activity of influenza recombinant and mutant strains.

Authors: W J Bean; R W Simpson
Journal: J Virol Date: 1975-09 Impact factor: 5.103

10. Transcription of the influenza ribonucleic acid genome by a virion polymerase. I. Optimal conditions for in vitro activity of the ribonucleic acid-dependent ribonucleic acid polymerase.

Authors: D H Bishop; J F Obijeski; R W Simpson
Journal: J Virol Date: 1971-07 Impact factor: 5.103

6 in total

1. Characterization of a temperature-sensitive mutant in the RNA polymerase PB2 subunit gene of influenza A/WSN/33 virus.

Authors: K Yamanaka; N Ogasawara; M Ueda; H Yoshikawa; A Ishihama; K Nagata
Journal: Arch Virol Date: 1990 Impact factor: 2.574

2. The PB1 subunit alone can catalyze cRNA synthesis, and the PA subunit in addition to the PB1 subunit is required for viral RNA synthesis in replication of the influenza virus genome.

Authors: Y Nakagawa; K Oda; S Nakada
Journal: J Virol Date: 1996-09 Impact factor: 5.103