Literature DB >> 9972459

Cytochrome P450 in parasitic protozoa and helminths.

J Barrett1.   

Abstract

Cytochrome P450 has been demonstrated in flagellate and sporozoan Protozoa. In Plasmodium there is a correlation between chloroquine resistance and cytochrome P450 mono-oxygenase activity, but there is no evidence that the malarial parasite metabolises chloroquine by an oxidative mechanism. There is no evidence for cytochrome P450 in adult helminths (nematodes and platyhelminths) based on P450 content and mono-oxygenase activity with classical substrates, although low activities may be present in free-living larval stages.

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Year:  1998        PMID： 9972459     DOI： 10.1016/s0742-8413(98)10039-7

Source DB:  PubMed          Journal:  Comp Biochem Physiol C Pharmacol Toxicol Endocrinol        ISSN： 1367-8280


  10 in total

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Journal:  Parasitol Res       Date:  2003-12-03       Impact factor: 2.289

2.  The cytochrome P450 family in the parasitic nematode Haemonchus contortus.

Authors:  Roz Laing; David J Bartley; Alison A Morrison; Andrew Rezansoff; Axel Martinelli; Steven T Laing; John S Gilleard
Journal:  Int J Parasitol       Date:  2014-12-31       Impact factor: 3.981

3.  Griseofulvin impairs intraerythrocytic growth of Plasmodium falciparum through ferrochelatase inhibition but lacks activity in an experimental human infection study.

Authors:  Clare M Smith; Ante Jerkovic; Thy Thuc Truong; Simon J Foote; James S McCarthy; Brendan J McMorran
Journal:  Sci Rep       Date:  2017-02-08       Impact factor: 4.379

4.  Comparison of constitutive and thiabendazole-induced expression of five cytochrome P450 genes in fourth-stage larvae of Haemonchus contortus isolates with different drug susceptibility identifies one gene with high constitutive expression in a multi-resistant isolate.

Authors:  Esra Yilmaz; Sabrina Ramünke; Janina Demeler; Jürgen Krücken
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2017-10-07       Impact factor: 4.077

5.  Cytochrome P450 metabolism mediates low-temperature resistance in pinewood nematode.

Authors:  Bowen Wang; Xin Hao; Jiayao Xu; Buyong Wang; Wei Ma; Xuefeng Liu; Ling Ma
Journal:  FEBS Open Bio       Date:  2020-05-22       Impact factor: 2.693

6.  Polycyclic aromatic hydrocarbons in the cestode Oncomegas wageneri parasite of Mexican flounder Cyclopsetta chittendeni.

Authors:  Lilia C Soler-Jiménez; Emanuel Hernández-Núñez; Iván Velázquez-Abunader; Arturo Centeno-Chalé; Víctor M Vidal-Martínez
Journal:  Parasitol Res       Date:  2020-02-01       Impact factor: 2.289

7.  Trichuris suis and Oesophagostomum dentatum show different sensitivity and accumulation of fenbendazole, albendazole and levamisole in vitro.

Authors:  Tina V A Hansen; Peter Nejsum; Christian Friis; Annette Olsen; Stig Milan Thamsborg
Journal:  PLoS Negl Trop Dis       Date:  2014-04-03

8.  Functional characterization of a unique cytochrome P450 in Toxoplasma gondii.

Authors:  Xiao Zhang; Taotao Zhang; Jing Liu; Muzi Li; Yong Fu; Jianhai Xu; Qun Liu
Journal:  Oncotarget       Date:  2017-12-06

9.  Partial purification and characterization of glutathione S-transferase from the somatic tissue of Gastrothylax crumenifer (Trematoda: Digenea).

Authors:  Sakil Ahmed; Aamir Sohail; Sabiha Khatoon; Shabnam Khan; Mohammad Khalid Saifullah
Journal:  Vet World       Date:  2014-12-21

10.  A Whole Genome Re-Sequencing Based GWA Analysis Reveals Candidate Genes Associated with Ivermectin Resistance in Haemonchus contortus.

Authors:  Sawar Khan; Ayesha Nisar; Jianqi Yuan; Xiaoping Luo; Xueqin Dou; Fei Liu; Xiaochao Zhao; Junyan Li; Habib Ahmad; Sardar Azhar Mehmood; Xingang Feng
Journal:  Genes (Basel)       Date:  2020-03-28       Impact factor: 4.096
  10 in total

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