PURPOSE: To show the use of the polymerase chain reaction (PCR) in a granulomatous choroidal lesion to support a diagnosis of tuberculosis. DESIGN: Observational case report. TESTING: Nucleic acid target amplification of a choroidal specimen using PCR for detection of Mycobacterium tuberculosis was tested. MAIN OUTCOME MEASURES: Positive nucleic acid target amplification for M. tuberculosis in the ocular sample was measured. RESULTS: PCR was positive for M. tuberculosis with appropriate negative controls. CONCLUSIONS: PCR was thought to be a useful supportive technique in the diagnosis of choroidal tuberculosis.
PURPOSE: To show the use of the polymerase chain reaction (PCR) in a granulomatous choroidal lesion to support a diagnosis of tuberculosis. DESIGN: Observational case report. TESTING: Nucleic acid target amplification of a choroidal specimen using PCR for detection of Mycobacterium tuberculosis was tested. MAIN OUTCOME MEASURES: Positive nucleic acid target amplification for M. tuberculosis in the ocular sample was measured. RESULTS: PCR was positive for M. tuberculosis with appropriate negative controls. CONCLUSIONS: PCR was thought to be a useful supportive technique in the diagnosis of choroidal tuberculosis.
Authors: J Fernando Arevalo; Andres F Lasave; Turki Abdullah Al Ghamdi; Vishali Gupta; Igor Kozak; Hassan A Al Dhibi Journal: Graefes Arch Clin Exp Ophthalmol Date: 2019-06-08 Impact factor: 3.117
Authors: Eduardo F Marback; Epaminondas de Souza Mendes; Ricardo D Chagas Oliveira; Jignesh G Parikh; Narsing A Rao Journal: J Ophthalmic Inflamm Infect Date: 2010-11-17