Literature DB >> 23737572

Tubercular retinal vasculitis.

Maria Sara Patricio1, Joana Portelinha, Maria Picoto Passarinho, Marta Esteves Guedes.   

Abstract

Intraocular tuberculosis (TB) infection can have different clinical manifestations including retinal vasculitis. It more frequently involves the veins and is associated with retina haemorrhages and neovascularisation. The diagnosis may be difficult and presumptive being based on clinical findings and evidence of systemic TB infection. The authors present a case of a 61-year-old woman with blurred vision and floaters in her left eye for 6 years, associated with recurrent vitreous haemorrahages. A temporal branch retinal vein occlusion was presumed. Four years later her right eye was also involved. Her best-corrected visual acuity (BCVA) was 20/50 in both eyes. Fundoscopic examination showed bilateral venous occlusion with vascular staining on fluorescein angiography suggestive of vasculitis secondary to Eales Disease (ED). The interferon gamma release assay (IGRA-QuantiFERON-TB Gold) was positive and antituberculosis treatment (ATT) was started. Her final BCVA was 20/20 bilaterally, without recurrences over a follow-up of 15 months. The use of ATT is likely to reduce recurrent vitreous haemorrhages and eliminate future recurrences.

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Year:  2013        PMID: 23737572      PMCID: PMC3702819          DOI: 10.1136/bcr-2013-008924

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  14 in total

1.  Use of polymerase chain reaction in detection of Mycobacterium tuberculosis complex DNA from vitreous sample of Eales' disease.

Authors:  J Biswas; L Therese; H N Madhavan
Journal:  Br J Ophthalmol       Date:  1999-08       Impact factor: 4.638

2.  Recurrent intraocular hemorrhage in young adults (Eales' disease); treatment with continuous subconjunctival therapy with hydrocortisone.

Authors:  A J ELLIOT
Journal:  AMA Arch Ophthalmol       Date:  1959-05

3.  PCR-positive tubercular retinal vasculitis: clinical characteristics and management.

Authors:  A Gupta; V Gupta; S Arora; M R Dogra; P Bambery
Journal:  Retina       Date:  2001       Impact factor: 4.256

4.  Tuberculous uveitis: distribution of Mycobacterium tuberculosis in the retinal pigment epithelium.

Authors:  Narsing A Rao; Sindhu Saraswathy; Ronald E Smith
Journal:  Arch Ophthalmol       Date:  2006-12

5.  Tuberculous choroiditis diagnosed by chorioretinal endobiopsy.

Authors:  M J Barondes; W E Sponsel; T S Stevens; R D Plotnik
Journal:  Am J Ophthalmol       Date:  1991-10-15       Impact factor: 5.258

6.  Polymerase chain reaction for the detection of Mycobacterium tuberculosis in ocular tuberculosis.

Authors:  S Kotake; K Kimura; K Yoshikawa; Y Sasamoto; A Matsuda; T Nishikawa; N Fujii; H Matsuda
Journal:  Am J Ophthalmol       Date:  1994-06-15       Impact factor: 5.258

Review 7.  Extrapulmonary tuberculosis revisited: a review of experience at Boston City and other hospitals.

Authors:  S Alvarez; W R McCabe
Journal:  Medicine (Baltimore)       Date:  1984-01       Impact factor: 1.889

8.  Quantitative polymerase chain reaction for Mycobacterium tuberculosis in so-called Eales' disease.

Authors:  Rishiraj Singh; Pooja Toor; Swapnil Parchand; Kusum Sharma; Vishali Gupta; Amod Gupta
Journal:  Ocul Immunol Inflamm       Date:  2012-04-09       Impact factor: 3.070

9.  Choroidal tuberculosis diagnosed by polymerase chain reaction. A clinicopathologic case report.

Authors:  J D Bowyer; P D Gormley; R Seth; R N Downes; J Lowe
Journal:  Ophthalmology       Date:  1999-02       Impact factor: 12.079

Review 10.  Eales disease--an update.

Authors:  Jyotirmay Biswas; Tarun Sharma; Lingam Gopal; Hajib N Madhavan; K N Sulochana; S Ramakrishnan
Journal:  Surv Ophthalmol       Date:  2002 May-Jun       Impact factor: 6.048

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  1 in total

1.  Seizures in an immunocompromised adolescent: a case report.

Authors:  Vipula R Bataduwaarachchi; Nirmali Tissera
Journal:  J Med Case Rep       Date:  2015-08-28
  1 in total

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