Literature DB >> 9934478

O-(fluoresceinylmethyl)hydroxylamine (OFMHA): a fluorescent reagent for detection of damaged nucleic acids.

M Adamczyk1, P G Mattingly, J A Moore.   

Abstract

5- and 6-O-(Fluoresceinylmethyl)hydroxylamine (OFMHA, 5a, b) were prepared from the corresponding bis-pivaloyl-protected hydroxymethylfluoresceins (1a, b) in 50-70% yield. The hydroxylamine derivatives reacted smoothly with the abasic sites present in acid/heat stressed calf thymus DNA.

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Year:  1998        PMID: 9934478     DOI: 10.1016/s0960-894x(98)00658-1

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  3 in total

1.  Templated chemistry for monitoring damage and repair directly in duplex DNA.

Authors:  Seoung Ho Lee; Shenliang Wang; Eric T Kool
Journal:  Chem Commun (Camb)       Date:  2012-07-10       Impact factor: 6.222

2.  Sensitivity of Ru(bpy)2dppz2+ luminescence to DNA defects.

Authors:  Mi Hee Lim; Hang Song; Eric D Olmon; Elizabeth E Dervan; Jacqueline K Barton
Journal:  Inorg Chem       Date:  2009-06-15       Impact factor: 5.165

3.  Synthesis and Photophysical Properties of Fluorescein Esters as Potential Organic Semiconductor Materials.

Authors:  Gamal A E Mostafa; Abu Syed Mahajumi; Haitham AlRabiah; Adnan A Kadi; Yang Lu; A F M Motiur Rahman
Journal:  J Fluoresc       Date:  2021-07-21       Impact factor: 2.217

  3 in total

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