Literature DB >> 9934448

Coprophilin: an anticoccidial agent produced by a dung inhabiting fungus.

J G Ondeyka1, R A Giacobbe, G F Bills, C Cuadrillero, D Schmatz, M A Goetz, D L Zink, S B Singh.   

Abstract

Coprophilin, a decalin pentanedienoic acid methyl ester, was isolated from an unidentified fungus by bioassay guided separation. It inhibited (MIC = 1.5 microM) the growth of Eimeria tenella in an in vitro assay. The isolation, structure elucidation, absolute stereochemistry and biology are described.

Entities:  

Mesh:

Substances:

Year:  1998        PMID: 9934448     DOI: 10.1016/s0960-894x(98)00629-5

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  3 in total

1.  Isolation, structure, and HIV-1-integrase inhibitory activity of structurally diverse fungal metabolites.

Authors:  Sheo B Singh; Hiranthi Jayasuriya; Raymond Dewey; Jon D Polishook; Anne W Dombrowski; Deborah L Zink; Ziqiang Guan; Javier Collado; Gonzalo Platas; Fernando Pelaez; Peter J Felock; Daria J Hazuda
Journal:  J Ind Microbiol Biotechnol       Date:  2004-01-09       Impact factor: 3.346

2.  Lipid-Lowering Polyketides from the Fungus Penicillium Steckii HDN13-279.

Authors:  Guihong Yu; Shuai Wang; Lu Wang; Qian Che; Tianjiao Zhu; Guojian Zhang; Qianqun Gu; Peng Guo; Dehai Li
Journal:  Mar Drugs       Date:  2018-01-12       Impact factor: 5.118

3.  Elsinopirins A-D, Decalin Polyketides from the Ascomycete Elsinoё pyri.

Authors:  Frank Surup; Kathrin Pommerehne; Hans-Josef Schroers; Marc Stadler
Journal:  Biomolecules       Date:  2018-02-05
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.