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Literature DB >> 993335

Persistence of thromboxane A2-like material and platelet release-inducing activity in plasma.

Abstract

During the incubation of arachidonic acid with platelet-rich plasma, a persistent activity appeared that caused the release of [14C]5-hydroxytryptamine from indomethacin-treated platelets. By the time-course of its appearance and disappearance, this release-inducing activity could be dissociated from prostaglandin endoperoxides and associated with thromboxane A2-like material. This material persists in plasma because of its continued production and increased stability.

Entities: Chemical

Mesh：

Substances：

Year: 1976 PMID： 993335 PMCID： PMC333279 DOI： 10.1172/JCI108564

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

8 in total

Review 1. Prostaglandins and precursors in platelet function.

Authors: J B Smith; C M Ingerman; M J Silver
Journal: Ciba Found Symp Date: 1975

2. Formation of an intermediate in prostaglandin biosynthesis and its association with the platelet release reaction.

Authors: J B Smith; C Ingerman; J J Kocsis; M J Silver
Journal: J Clin Invest Date: 1974-05 Impact factor: 14.808

3. Effects of normal and aspirin platelets on defective secondary aggregation in the Hermansky-Pudlak syndrome. A test for storage pool deficient platelets.

Authors: J G White; C J Witkop
Journal: Am J Pathol Date: 1972-07 Impact factor: 4.307

4. Arachidonic acid-induced human platelet aggregation and prostaglandin formation.

Authors: M J Silver; J B Smith; C Ingerman; J J Kocsis
Journal: Prostaglandins Date: 1973-12

5. Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation.

Authors: M Hamberg; J Svensson; T Wakabayashi; B Samuelsson
Journal: Proc Natl Acad Sci U S A Date: 1974-02 Impact factor: 11.205

6. Physiological role of an endoperoxide in human platelets: hemostatic defect due to platelet cyclo-oxygenase deficiency.

Authors: C Malmsten; M Hamberg; J Svensson; B Samuelsson
Journal: Proc Natl Acad Sci U S A Date: 1975-04 Impact factor: 11.205

7. Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

Authors: M Hamberg; J Svensson; B Samuelsson
Journal: Proc Natl Acad Sci U S A Date: 1975-08 Impact factor: 11.205

8. Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets.

Authors: M Hamberg; B Samuelsson
Journal: Proc Natl Acad Sci U S A Date: 1974-09 Impact factor: 11.205

8 in total

7 in total

1. Release of platelet constituents by monosodium urate crystals.

Authors: M H Ginsberg; F Kozin; M O'Malley; D J McCarty
Journal: J Clin Invest Date: 1977-11 Impact factor: 14.808

2. Role of proaggregatory and antiaggregatory prostaglandins in hemostasis. Studies with combined thromboxane synthase inhibition and thromboxane receptor antagonism.

Authors: P Gresele; J Arnout; H Deckmyn; E Huybrechts; G Pieters; J Vermylen
Journal: J Clin Invest Date: 1987-11 Impact factor: 14.808

3. Neutrophil aggregation and degranulation. Effect of arachidonic acid.

Authors: J T O'Flaherty; H J Showell; E L Becker; P A Ward
Journal: Am J Pathol Date: 1979-05 Impact factor: 4.307

4. Effect of racemic ibuprofen dose on the magnitude and duration of platelet cyclo-oxygenase inhibition: relationship between inhibition of thromboxane production and the plasma unbound concentration of S(+)-ibuprofen.

Authors: A M Evans; R L Nation; L N Sansom; F Bochner; A A Somogyi
Journal: Br J Clin Pharmacol Date: 1991-02 Impact factor: 4.335