A new approach to optimal dynamic therapy planning.

Therapy planning is a very complex task. One of its crucial aspect is the derivation of therapeutic plans taking into account the dynamic aspect of the decision problem. This paper deals with dynamic decision problems using Influence Views, a novel graphical formalism based on Markov Decision Processes (MDPs) framework, in order to solve decision problems in which the optimal choice has to be revised periodically in accordance to the evolution of the patient's conditions. The proposed methodology has been applied to the plan of the prophylaxis in patients affected by a mild Hereditary Spherocytosis.