Literature DB >> 9925545

Mycobacteriocidal action of exogenous nitric oxide.

R Long1, B Light, J A Talbot.   

Abstract

We tested the hypothesis that exposure of extracellular Mycobacterium tuberculosis to low concentrations (< 100 ppm) of nitric oxide (NO) for short periods (24 h or less) will result in microbial killing. We observed that NO had both dose- and time-dependent cidal effects that were very significant by two-way analysis of variance (F ratios of 13.4 [P < 0.001] and 98.1 [P < 0.0001], respectively). Conceivably, extracellular bacilli in patients with pulmonary tuberculosis might be vulnerable to exogenous NO.

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Year:  1999        PMID： 9925545      PMCID： PMC89090     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  18 in total

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  30 in total

1.  Inhibitory effect of NO-releasing ciprofloxacin (NCX 976) on Mycobacterium tuberculosis survival.

Authors:  R Ciccone; F Mariani; A Cavone; T Persichini; G Venturini; E Ongini; V Colizzi; M Colasanti
Journal:  Antimicrob Agents Chemother       Date:  2003-07       Impact factor: 5.191

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Authors:  Richard Long; Richard Jones; James Talbot; Irvin Mayers; James Barrie; Michael Hoskinson; Bruce Light
Journal:  Antimicrob Agents Chemother       Date:  2005-03       Impact factor: 5.191

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Journal:  Proc Am Thorac Soc       Date:  2006-04

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Authors:  Shuangping Shi; Sabine Ehrt
Journal:  Infect Immun       Date:  2006-01       Impact factor: 3.441

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Journal:  Nat Microbiol       Date:  2021-07-22       Impact factor: 17.745

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Authors:  Philip O'Reilly; Judy M Hickman-Davis; Philip McArdle; K Randall Young; Sadis Matalon
Journal:  Mol Cell Biochem       Date:  2002 May-Jun       Impact factor: 3.396

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Authors:  Hugues Ouellet; Jérôme Lang; Manon Couture; Paul R Ortiz de Montellano
Journal:  Biochemistry       Date:  2009-02-10       Impact factor: 3.162

8.  Direct EPR Detection of Nitric Oxide in Mice Infected with the Pathogenic Mycobacterium Mycobacterium tuberculosis.

Authors:  Anatoly F Vanin; Raisa P Selitskaya; Vladimir A Serezhenkov; Galina N Mozhokina
Journal:  Appl Magn Reson       Date:  2009-12-03       Impact factor: 0.831

9.  Nitric Oxide Synthesis is Modulated by 1,25-Dihydroxyvitamin D3 and Interferon-gamma in Human Macrophages after Mycobacterial Infection.

Authors:  Ji-Sook Lee; Chul-Su Yang; Dong-Min Shin; Jae-Min Yuk; Ji-Woong Son; Eun-Kyeong Jo
Journal:  Immune Netw       Date:  2009-10-30       Impact factor: 6.303

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Authors:  Nadia L Ferrer; Ana B Gomez; Olivier Neyrolles; Brigitte Gicquel; Carlos Martin
Journal:  PLoS One       Date:  2010-09-24       Impact factor: 3.240
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