Literature DB >> 9921606

Robust and realistic approaches to carry-over.

S Senn1, D Lambrou.   

Abstract

The relationship between choice of model for carry-over and choice of efficient cross-over design is studied in particular with reference to two treatment designs in four periods and two sequences. The effect of model miss-specification is also examined. It is concluded that previous claims regarding efficient designs are not necessarily reasonable.

Mesh:

Year:  1998        PMID: 9921606     DOI: 10.1002/(sici)1097-0258(19981230)17:24<2849::aid-sim955>3.0.co;2-o

Source DB:  PubMed          Journal:  Stat Med        ISSN: 0277-6715            Impact factor:   2.373


  2 in total

1.  Construction of the Design Matrix for Generalized Linear Mixed-Effects Models in the Context of Clinical Trials of Treatment Sequences.

Authors:  Francisco J Diaz
Journal:  Rev Colomb Estad       Date:  2018-07

2.  Maximin Efficiencies under Treatment-Dependent Costs and Outcome Variances for Parallel, AA/BB, and AB/BA Designs.

Authors:  Math J J M Candel
Journal:  Comput Math Methods Med       Date:  2018-10-01       Impact factor: 2.238

  2 in total

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