Literature DB >> 9920435

Melanoma is not caused by sunlight.

A J Christophers.   

Abstract

When comparisons are made of cutaneous melanoma with cutaneous squamous cell cancer (SCC) and basal cell cancer (BCC) of the skin with respect to age dependence, sex ratio, distribution on the body, association with sun exposure, and variation with latitude, it is clear that SCC is due almost entirely to sun exposure, that BCC is partly due to sun exposure, and that melanoma is not due to sun exposure. For melanoma, it is only latitudinal variation that favours the hypothesis of sun exposure causation. However, an examination of the latitudinal variation of SCC incidence reveals that this is several fold greater than can be accounted for by variation of exposure to UV-B. The other factor operating appears to be skin temperature. For melanoma, it is postulated that the latter factor by itself may suffice to account for the observed variation with latitude. The higher incidence of melanoma in the higher social classes and its increasing incidence with age may be readily explained by the hypothesis that melanoma incidence increases with increase in skin temperature.

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Year:  1998        PMID: 9920435     DOI: 10.1016/s0027-5107(98)00182-1

Source DB:  PubMed          Journal:  Mutat Res        ISSN: 0027-5107            Impact factor:   2.433


  4 in total

Review 1.  Prevention of non-melanoma skin cancer.

Authors:  S P Stratton
Journal:  Curr Oncol Rep       Date:  2001-07       Impact factor: 5.075

2.  Sex differences in the association of cutaneous melanoma incidence rates and geographic ultraviolet light exposure.

Authors:  Feng Liu-Smith; Ahmed Majid Farhat; Anthony Arce; Argyrios Ziogas; Thomas Taylor; Zi Wang; Vandy Yourk; Jing Liu; Jun Wu; Archana J McEligot; Hoda Anton-Culver; Frank L Meyskens
Journal:  J Am Acad Dermatol       Date:  2016-10-26       Impact factor: 11.527

3.  Identification of master regulator genes of UV response and their implications for skin carcinogenesis.

Authors:  Yao Shen; Gabriel Chan; Michael Xie; Wangyong Zeng; Liang Liu
Journal:  Carcinogenesis       Date:  2019-07-04       Impact factor: 4.944

4.  A partial gene deletion of SLC45A2 causes oculocutaneous albinism in Doberman pinscher dogs.

Authors:  Paige A Winkler; Kara R Gornik; David T Ramsey; Richard R Dubielzig; Patrick J Venta; Simon M Petersen-Jones; Joshua T Bartoe
Journal:  PLoS One       Date:  2014-03-19       Impact factor: 3.240

  4 in total

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