Literature DB >> 9915499

The genetics of cancer--a 3D model.

K A Cole1, D B Krizman, M R Emmert-Buck.   

Abstract

Gene expression microarrays hold great promise for studies of human disease states. There are significant technical issues specific to utilizing clinical tissue samples which have yet to be rigorously addressed and completely overcome. Precise, quantitative measurement of gene expression profiles from specific cell populations is at hand, offering the scientific community the first comprehensive view of the in vivo molecular anatomy of normal cells and their diseased counterparts. Here, we propose a model for integrating-in three dimensions-expression data obtained using the microarray.

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Year:  1999        PMID： 9915499     DOI： 10.1038/4466

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  25 in total

Review 1.  Molecular profiling of clinical tissues specimens: feasibility and applications.

Authors:  M R Emmert-Buck; R L Strausberg; D B Krizman; M F Bonaldo; R F Bonner; D G Bostwick; M R Brown; K H Buetow; R F Chuaqui; K A Cole; P H Duray; C R Englert; J W Gillespie; S Greenhut; L Grouse; L W Hillier; K S Katz; R D Klausner; V Kuznetzov; A E Lash; G Lennon; W M Linehan; L A Liotta; M A Marra; P J Munson; D K Ornstein; V V Prabhu; C Prang; G D Schuler; M B Soares; C M Tolstoshev; C D Vocke; R H Waterston
Journal:  J Mol Diagn       Date:  2000-05       Impact factor: 5.568

Review 2.  Molecular profiling of clinical tissue specimens: feasibility and applications.

Authors:  M R Emmert-Buck; R L Strausberg; D B Krizman; M F Bonaldo; R F Bonner; D G Bostwick; M R Brown; K H Buetow; R F Chuaqui; K A Cole; P H Duray; C R Englert; J W Gillespie; S Greenhut; L Grouse; L W Hillier; K S Katz; R D Klausner; V Kuznetzov; A E Lash; G Lennon; W M Linehan; L A Liotta; M A Marra; P J Munson; D K Ornstein; V V Prabhu; C Prange; G D Schuler; M B Soares; C M Tolstoshev; C D Vocke; R H Waterston
Journal:  Am J Pathol       Date:  2000-04       Impact factor: 4.307

Review 3.  Laser capture microdissection: beyond functional genomics to proteomics.

Authors:  N L Simone; C P Paweletz; L Charboneau; E F Petricoin; L A Liotta
Journal:  Mol Diagn       Date:  2000-12

4.  In silico cloning of novel endothelial-specific genes.

Authors:  L Huminiecki; R Bicknell
Journal:  Genome Res       Date:  2000-11       Impact factor: 9.043

5.  Evaluation of non-formalin tissue fixation for molecular profiling studies.

Authors:  John W Gillespie; Carolyn J M Best; Verena E Bichsel; Kristina A Cole; Susan F Greenhut; Stephen M Hewitt; Mamoun Ahram; Yvonne B Gathright; Maria J Merino; Robert L Strausberg; Jonathan I Epstein; Stanley R Hamilton; Gallya Gannot; Galina V Baibakova; Valerie S Calvert; Michael J Flaig; Rodrigo F Chuaqui; Judi C Herring; John Pfeifer; Emmanuel F Petricoin; W Marston Linehan; Paul H Duray; G Steven Bova; Michael R Emmert-Buck
Journal:  Am J Pathol       Date:  2002-02       Impact factor: 4.307

6.  Tracing the tumor lineage.

Authors:  Nicholas E Navin; James Hicks
Journal:  Mol Oncol       Date:  2010-05-05       Impact factor: 6.603

7.  Squamous Cell Carcinoma - Similarities and Differences among Anatomical Sites.

Authors:  Wusheng Yan; Ignacio I Wistuba; Michael R Emmert-Buck; Heidi S Erickson
Journal:  Am J Cancer Res       Date:  2011-01-01       Impact factor: 6.166

8.  Integrin gene expression profiles of human hepatocellular carcinoma.

Authors:  Lian-Xin Liu; Hong-Chi Jiang; Zhi-Hua Liu; Jing Zhou; Wei-Hui Zhang; An-Long Zhu; Xiu-Qin Wang; Min Wu
Journal:  World J Gastroenterol       Date:  2002-08       Impact factor: 5.742

9.  Inferring tumor progression from genomic heterogeneity.

Authors:  Nicholas Navin; Alexander Krasnitz; Linda Rodgers; Kerry Cook; Jennifer Meth; Jude Kendall; Michael Riggs; Yvonne Eberling; Jennifer Troge; Vladimir Grubor; Dan Levy; Pär Lundin; Susanne Månér; Anders Zetterberg; James Hicks; Michael Wigler
Journal:  Genome Res       Date:  2009-11-10       Impact factor: 9.043

10.  Integrating complex genomic datasets and tumour cell sensitivity profiles to address a 'simple' question: which patients should get this drug?

Authors:  Cyril Benes; Jeff Settleman
Journal:  BMC Med       Date:  2009-12-14       Impact factor: 8.775
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