| Literature DB >> 9915493 |
E Southern1, K Mir, M Shchepinov.
Abstract
The structural features of nucleic acid probes tethered to a solid support and the molecular basis of their interaction with targets in solution have direct implication for the hybridization process. We discuss how arrays of oligonucleotides provide powerful tools to study the molecular basis of these interactions on a scale which is impossible using conventional analysis.Entities:
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Year: 1999 PMID: 9915493 DOI: 10.1038/4429
Source DB: PubMed Journal: Nat Genet ISSN: 1061-4036 Impact factor: 38.330