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Literature DB >> 9914223

Susceptibility to lupus nephritis in the NZB/W model system.

Abstract

Advances in genetic mapping have resulted in the identification of multiple lupus susceptibility loci in the NZB/W mouse model. The analysis of congenic strains carrying these loci is now providing functional data on their role in lupus pathogenesis and is paving the way to the identification of the susceptibility genes and their molecular characterization.

Entities: Disease Species

Mesh：

Year: 1998 PMID： 9914223 DOI： 10.1016/s0952-7915(98)80094-0

Source DB: PubMed Journal: Curr Opin Immunol ISSN： 0952-7915 Impact factor: 7.486

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Cited

21 in total

Review 1. Pathogenesis of systemic lupus erythematosus revisited 2011: end organ resistance to damage, autoantibody initiation and diversification, and HLA-DR.

Authors: Shu Man Fu; Umesh S Deshmukh; Felicia Gaskin
Journal: J Autoimmun Date: 2011-06-01 Impact factor: 7.094

2. Lupus at the molecular level.

Authors: Mayami Sengupta; Laurence Morel
Journal: Protein Cell Date: 2011-12 Impact factor: 14.870

3. Models of chronic kidney disease.

Authors: Hai-Chun Yang; Yiqin Zuo; Agnes B Fogo
Journal: Drug Discov Today Dis Models Date: 2010

4. A peptide based on the complementarity-determining region 1 of an autoantibody ameliorates lupus by up-regulating CD4+CD25+ cells and TGF-beta.

Authors: Amir Sharabi; Heidy Zinger; Maya Zborowsky; Zev M Sthoeger; Edna Mozes
Journal: Proc Natl Acad Sci U S A Date: 2006-05-30 Impact factor: 11.205

Susceptibility to lupus nephritis in the NZB/W model system.

Review 1. Pathogenesis of systemic lupus erythematosus revisited 2011: end organ resistance to damage, autoantibody initiation and diversification, and HLA-DR.

2. Lupus at the molecular level.

3. Models of chronic kidney disease.

4. A peptide based on the complementarity-determining region 1 of an autoantibody ameliorates lupus by up-regulating CD4+CD25+ cells and TGF-beta.

Review 5. The riddle of the dual expression of IgM and IgD.

6. The endogenous adjuvant squalene can induce a chronic T-cell-mediated arthritis in rats.

Review 7. Chronic kidney disease-associated cardiovascular disease: scope and limitations of animal models.

8. Major peptide autoepitopes for nucleosome-specific T cells of human lupus.

Review 9. Dysregulation of T Follicular Helper Cells in Lupus.

Review 10. Chance, genetics, and the heterogeneity of disease and pathogenesis in systemic lupus erythematosus.