| Literature DB >> 21286234 |
Hai-Chun Yang1, Yiqin Zuo, Agnes B Fogo.
Abstract
Chronic kidney diseases result from recurrent or progressive injuries in glomeruli, tubules, interstitium and/or vasculature. In order to study pathogenesis, mechanisms and effects of interventions, many animal models have been developed, including spontaneous, genetic and induced models. However, these models do not exactly simulate human diseases, and most of them are strain, gender or age dependent. We review key information on various rodent models of chronic kidney diseases.Entities:
Year: 2010 PMID: 21286234 PMCID: PMC3030258 DOI: 10.1016/j.ddmod.2010.08.002
Source DB: PubMed Journal: Drug Discov Today Dis Models ISSN: 1740-6757