Ocular hypertension. I. The clinical course during ten years without therapy. Aqueous humour dynamics.

An initial group of 152 subjects with moderate ocular hypertension constituted the basic material of the present study. Antiglaucoma treatment was started in 8 men and in 6 women. A remaining group of 92 subjects were kept under clinical observation for ten years without antiglaucomatous therapy and without any evidence of progressive disc cupping or field defects. The intraocular pressure as well as the outflow facility showed a tendency to decrease with time, which was assumed to indicate a reduction in aqueous flow with increasing age. The tomographic findings support the view that the moderately elevated intraocular pressure is mainly due to an increased rate of aqueous flow.