Literature DB >> 9891944

Hypolipidemic activity of three indigenous drugs in experimentally induced atherosclerosis.

H P Shaila1, S L Udupa, A L Udupa.   

Abstract

The effect of orally administered indigenous drugs Terminalia arjuna, T. belerica and T. chebula were investigated on experimental atherosclerosis. Rabbits were fed a cholesterol-rich diet to induce atherosclerosis. The three drugs were fed along with cholesterol. At the end of the experimental period the animals were killed and their plasma and tissue lipid components estimated. Atherosclerotic lesions of the aorta were examined histologically. T. arjuna was found to be the most potent hypolipidemic agent and induced partial inhibition of rabbit atheroma. The results indicate that T. arjuna may play an anti-atherogenic role.

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Year:  1998        PMID: 9891944     DOI: 10.1016/s0167-5273(98)00281-2

Source DB:  PubMed          Journal:  Int J Cardiol        ISSN: 0167-5273            Impact factor:   4.164


  11 in total

1.  Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases: "reverse pharmacology" and "bedside to bench" approach.

Authors:  Bharat B Aggarwal; Sahdeo Prasad; Simone Reuter; Ramaswamy Kannappan; Vivek R Yadev; Byoungduck Park; Ji Hye Kim; Subash C Gupta; Kanokkarn Phromnoi; Chitra Sundaram; Seema Prasad; Madan M Chaturvedi; Bokyung Sung
Journal:  Curr Drug Targets       Date:  2011-10       Impact factor: 3.465

2.  Preventive effect of Terminalia bellirica on obesity and metabolic disorders in spontaneously obese type 2 diabetic model mice.

Authors:  Hiroko Makihara; Tsutomu Shimada; Eriko Machida; Masatomi Oota; Rika Nagamine; Masahito Tsubata; Kaoru Kinoshita; Kunio Takahashi; Masaki Aburada
Journal:  J Nat Med       Date:  2011-11-22       Impact factor: 2.343

Review 3.  The medicinal properties and phytochemistry of plants of the genus Terminalia (Combretaceae).

Authors:  I E Cock
Journal:  Inflammopharmacology       Date:  2015-07-31       Impact factor: 4.473

4.  Protective effect of Terminalia chebula against lysosomal enzyme alterations in isoproterenol-induced cardiac damage in rats.

Authors:  Subramaniyan Suchalatha; Chennam Srinivasulu Shyamala Devi
Journal:  Exp Clin Cardiol       Date:  2005

5.  Effect of crude extract of Bombyx mori coccoons in hyperlipidemia and atherosclerosis.

Authors:  Mir Mahdi Ali; Sarasa Bharati A Arumugam
Journal:  J Ayurveda Integr Med       Date:  2011-04

6.  Anti-Atherogenic Activity of Ethanolic Fraction of Terminalia arjuna Bark on Hypercholesterolemic Rabbits.

Authors:  Saravanan Subramaniam; Ramachandran Subramaniam; Suja Rajapandian; Subasini Uthrapathi; Victor Rajamanickam Gnanamanickam; Govinda Prasad Dubey
Journal:  Evid Based Complement Alternat Med       Date:  2011-03-20       Impact factor: 2.629

7.  Terminalia bellirica (Gaertn.) Roxb. Extract and Gallic Acid Attenuate LPS-Induced Inflammation and Oxidative Stress via MAPK/NF-κB and Akt/AMPK/Nrf2 Pathways.

Authors:  Miori Tanaka; Yoshimi Kishimoto; Mizuho Sasaki; Akari Sato; Tomoyasu Kamiya; Kazuo Kondo; Kaoruko Iida
Journal:  Oxid Med Cell Longev       Date:  2018-11-08       Impact factor: 6.543

8.  Possible mechanisms of hypotension produced 70% alcoholic extract of Terminalia arjuna (L.) in anaesthetized dogs.

Authors:  Srinivas Nammi; Rambabu Gudavalli; Behara S Ravindra Babu; Durga S Lodagala; Krishna M Boini
Journal:  BMC Complement Altern Med       Date:  2003-10-16       Impact factor: 3.659

9.  Studies on two polyherbal formulations (ZPTO and ZTO) for comparison of their antidyslipidemic, antihypertensive and endothelial modulating activities.

Authors:  Nauman Aziz; Malik Hassan Mehmood; Anwarul-Hassan Gilani
Journal:  BMC Complement Altern Med       Date:  2013-12-26       Impact factor: 3.659

10.  Terminalia bellirica Extract Inhibits Low-Density Lipoprotein Oxidation and Macrophage Inflammatory Response in Vitro.

Authors:  Miori Tanaka; Yoshimi Kishimoto; Emi Saita; Norie Suzuki-Sugihara; Tomoyasu Kamiya; Chie Taguchi; Kaoruko Iida; Kazuo Kondo
Journal:  Antioxidants (Basel)       Date:  2016-06-14
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