Literature DB >> 9889236

Evaluation of AMPLILINK software for the COBAS AMPLICOR system.

H H Kessler1, D Jungkind, E Stelzl, S Direnzo, S K Vellimedu, K Pierer, B Santner, E Marth.   

Abstract

The use of AMPLILINK version 1.0 software was evaluated for the operation and control of one COBAS AMPLICOR instrument and for two COBAS AMPLICOR instruments run simultaneously to perform and detect nucleic acid amplification reactions. A total of 3,384 results were analyzed. The initial accuracy of the results was 99.91%. Three errors of omission of transfer of data from the COBAS AMPLICOR to the AMPLILINK system were observed. Two of these errors were from a single specimen, where both the analyte and internal control results were not transmitted. These errors did not interfere with the correctness of any other data. There were no interruptions of runs, and no data were mixed. AMPLILINK increased convenience, saved labor, and was found to be a very useful addition for clinical laboratories performing molecular-diagnostic procedures with the COBAS AMPLICOR system.

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Mesh：

Year:  1999        PMID： 9889236      PMCID： PMC84332     

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  11 in total

1.  Comparison of three commercially available amplification assays, AMP CT, LCx, and COBAS AMPLICOR, for detection of Chlamydia trachomatis in first-void urine.

Authors:  W H Goessens; J W Mouton; W I van der Meijden; S Deelen; T H van Rijsoort-Vos; N Lemmens-den Toom; H A Verbrugh; R P Verkooyen
Journal:  J Clin Microbiol       Date:  1997-10       Impact factor: 5.948

2.  An internal control for routine diagnostic PCR: design, properties, and effect on clinical performance.

Authors:  M Rosenstraus; Z Wang; S Y Chang; D DeBonville; J P Spadoro
Journal:  J Clin Microbiol       Date:  1998-01       Impact factor: 5.948

3.  Evaluation of the COBAS AMPLICOR MTB system.

Authors:  T Bodmer; A Gurtner; M Scholkmann; L Matter
Journal:  J Clin Microbiol       Date:  1997-06       Impact factor: 5.948

4.  COBAS AMPLICOR: fully automated RNA and DNA amplification and detection system for routine diagnostic PCR.

Authors:  N DiDomenico; H Link; R Knobel; T Caratsch; W Weschler; Z G Loewy; M Rosenstraus
Journal:  Clin Chem       Date:  1996-12       Impact factor: 8.327

5.  International collaborative study on the second EUROHEP HCV-RNA reference panel.

Authors:  M Damen; H T Cuypers; H L Zaaijer; H W Reesink; W P Schaasberg; W H Gerlich; H G Niesters; P N Lelie
Journal:  J Virol Methods       Date:  1996-04-26       Impact factor: 2.014

6.  Evaluation of automated COBAS AMPLICOR PCR system for detection of several infectious agents and its impact on laboratory management.

Authors:  D Jungkind; S Direnzo; K G Beavis; N S Silverman
Journal:  J Clin Microbiol       Date:  1996-11       Impact factor: 5.948

7.  Preventing false positives: quantitative evaluation of three protocols for inactivation of polymerase chain reaction amplification products.

Authors:  P N Rys; D H Persing
Journal:  J Clin Microbiol       Date:  1993-09       Impact factor: 5.948

8.  Comparison of Roche Cobas Amplicor and Abbott LCx for the rapid detection of Chlamydia trachomatis in specimens from high-risk patients.

Authors:  O Steingrímsson; K Jónsdóttir; J H Olafsson; S M Karlsson; R Pálsdóttir; S Davídsson
Journal:  Sex Transm Dis       Date:  1998-01       Impact factor: 2.830

9.  Performance of the automated COBAS AMPLICOR system for the detection of hepatitis C virus RNA.

Authors:  H H Kessler; E A Dragon; K Pierer; B I Santner; Y Liao; D Stünzner; E Stelzl; E Marth
Journal:  Clin Diagn Virol       Date:  1997-02

10.  Reliability of polymerase chain reaction for detection of hepatitis C virus.

Authors:  H L Zaaijer; H T Cuypers; H W Reesink; I N Winkel; G Gerken; P N Lelie
Journal:  Lancet       Date:  1993-03-20       Impact factor: 79.321
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  2 in total

1.  Laboratory evaluation of the Liat HIV Quant (IQuum) whole-blood and plasma HIV-1 viral load assays for point-of-care testing in South Africa.

Authors:  Lesley Scott; Natasha Gous; Sergio Carmona; Wendy Stevens
Journal:  J Clin Microbiol       Date:  2015-03-04       Impact factor: 5.948

2.  Feasibility of HIV point-of-care tests for resource-limited settings: challenges and solutions.

Authors:  Wendy Stevens; Natasha Gous; Nathan Ford; Lesley E Scott
Journal:  BMC Med       Date:  2014-09-08       Impact factor: 8.775
  2 in total

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