Literature DB >> 9889139

Inkjet dispensing technology: applications in drug discovery.

A V Lemmo1, D J Rose, T C Tisone.   

Abstract

The past year has seen significant advances in the reduction to practice of inkjet dispensing technology in drug discovery applications. Although much of the work in this area has been done by relatively few 'early innovators', broader acceptance of the feasibility of the use of inkjet dispensing is on the rise. Of the three main areas of drug discovery - genomics, high-throughput screening, and combinatorial chemistry - high-throughput screening has had the most applications to date. The burgeoning field of genomics has seen rapid incorporation of technologies that enable miniaturization of gene expression experiments. Inkjet dispensing has a clear role in this effort. Finally, as the miniaturization needs of combinatorial chemistry become more clear, inkjet dispensing technology will potentially play a role.

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Year:  1998        PMID: 9889139     DOI: 10.1016/s0958-1669(98)80139-0

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN: 0958-1669            Impact factor:   9.740


  4 in total

Review 1.  Microarrays under the microscope.

Authors:  S E Wildsmith; F J Elcock
Journal:  Mol Pathol       Date:  2001-02

2.  Tunable resistive m-dPEG acid patterns on polyelectrolyte multilayers at physiological conditions: template for directed deposition of biomacromolecules.

Authors:  Srivatsan Kidambi; Christina Chan; Ilsoon Lee
Journal:  Langmuir       Date:  2007-12-01       Impact factor: 3.882

3.  An optical approach for the determination of droplet volumes in nanodispensing.

Authors:  Kerstin Thurow; Thomas Krüger; Norbert Stoll
Journal:  J Autom Methods Manag Chem       Date:  2009-05-04

Review 4.  Automated analytical microarrays: a critical review.

Authors:  Michael Seidel; Reinhard Niessner
Journal:  Anal Bioanal Chem       Date:  2008-05-27       Impact factor: 4.142

  4 in total

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