Literature DB >> 98783

Behavioural effects of methylphenidate in 6-hydroxydopamine-treated neonatal rats.

S M Eastgate, J J Wright, J S Werry.   

Abstract

Neonatal rats treated at 7 days of age with 6-hydroxydopamine show normal levels of activity during maturation, but less hyperactivity than normals do when additionally treated with methylphenidate hydrochloride between 14 and 22 days of age. Comparison of these results with those of other workers suggests that several experimental variables must be controlled precisely if reproducible results analogous to the disturbed behaviour of children with minimal brain dysfunction (MBD) are to be obtained.

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Year:  1978        PMID： 98783     DOI： 10.1007/bf00426899

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  15 in total

1.  A GENERAL PURPOSE ACTIVITY RECORDER WITH VARIABLE SENSITIVITY.

Authors:  J D DAVIS; G D ELLISON
Journal:  J Exp Anal Behav       Date:  1964-01       Impact factor: 2.468

2.  THE EFFECTS OF METHYLPHENIDATE ON SYMPTOMATOLOGY AND LEARNING IN DISTURBED CHILDREN.

Authors:  C K CONNERS; L EISENBERG
Journal:  Am J Psychiatry       Date:  1963-11       Impact factor: 18.112

3.  Selective brain dopamine depletion in developing rats: an experimental model of minimal brain dysfunction.

Authors:  B A Shaywitz; R D Yager; J H Klopper
Journal:  Science       Date:  1976-01-23       Impact factor: 47.728

4.  Comparative studies of various amphetamine analogues demonstrating different interactions with the metabolism of the catecholamines in the brain.

Authors:  J Scheel-Krüger
Journal:  Eur J Pharmacol       Date:  1971       Impact factor: 4.432

5.  Blockage of amphetamine induced motor stimulation and stereotypy in the adult rat following neonatal treatment with 6-hydroxydopamine.

Authors:  I Creese; S D Iversen
Journal:  Brain Res       Date:  1973-06-15       Impact factor: 3.252

6.  The involvement of dopaminergic systems with the stereotyped behaviour patterns induced by methylphenidate.

Authors:  B Costall; R J Naylor
Journal:  J Pharm Pharmacol       Date:  1974-01       Impact factor: 3.765

7.  The effects of pentobarbital on the fate of intracisternally administered norepinephrine-H3.

Authors:  S M Schanberg; J J Schildkraut; I J Kopin
Journal:  J Pharmacol Exp Ther       Date:  1967-08       Impact factor: 4.030

8.  The effects of methylphenidate (Ritalin) on the motor skills and behavior of children with learning problems.

Authors:  R M Knights; G G Hinton
Journal:  J Nerv Ment Dis       Date:  1969-06       Impact factor: 2.254

9.  Developmental characteristics of brain catecholamines and tyrosine hydroxylase in the rat: effects of 6-hydroxydopamine.

Authors:  G R Breese; T D Traylor
Journal:  Br J Pharmacol       Date:  1972-02       Impact factor: 8.739

10.  Attenuation of amphetamine-induced motor stimulation and stereotypy by 6-hydroxydopamine in the rat.

Authors:  H C Fibiger; H P Fibiger; A P Zis
Journal:  Br J Pharmacol       Date:  1973-04       Impact factor: 8.739
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  9 in total

Review 1.  A controlled study of Tourette syndrome. VII. Summary: a common genetic disorder causing disinhibition of the limbic system.

Authors:  D E Comings
Journal:  Am J Hum Genet       Date:  1987-11       Impact factor: 11.025

2.  Unilateral neonatal intracerebroventricular 6-hydroxydopamine administration in rats: I. Effects on spontaneous and drug-induced rotational behaviour and on postmortem monoamine levels.

Authors:  J Luthman; M Herrera-Marschitz; E Lindqvist
Journal:  Psychopharmacology (Berl)       Date:  1994-12       Impact factor: 4.530

3.  Unilateral neonatal intracerebroventricular 6-hydroxydopamine administration in rats: II. Effects on extracellular monoamine, acetylcholine and adenosine levels monitored with in vivo microdialysis.

Authors:  M Herrera-Marschitz; J Luthman; S Ferré
Journal:  Psychopharmacology (Berl)       Date:  1994-12       Impact factor: 4.530

4.  Functional deficits following neonatal dopamine depletion and isolation housing: circular water maze acquisition under pre-exposure conditions and motor activity.

Authors:  Trevor Archer; Tomás Palomo; Anders Fredriksson
Journal:  Neurotox Res       Date:  2002 Aug-Sep       Impact factor: 3.911

5.  An evaluation of the young dopamine-lesioned rat as an animal model for minimal brain dysfunction (MBD).

Authors:  R E Thieme; H Dijkstra; J C Stoof
Journal:  Psychopharmacology (Berl)       Date:  1980-02       Impact factor: 4.530

6.  Behavioural supersensitivity following neonatal 6-hydroxydopamine: attenuation by MK-801.

Authors:  T Archer; Anders Fredriksson
Journal:  Neurotox Res       Date:  2007-09       Impact factor: 3.911

7.  Effects of neonatal 6-hydroxydopamine treatment on catecholamine levels and behavior during development and adulthood.

Authors:  J L Fobes; M E Olds
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530

8.  Neonatal 6-hydroxydopamine-induced hypo/hyperactivity: blockade by dopamine reuptake inhibitors and effect of acute D-amphetamine.

Authors:  Trevor Archer; Tomas Palomo; Anders Fredriksson
Journal:  Neurotox Res       Date:  2002-05       Impact factor: 3.911

9.  Intraventricular 6-hydroxydopamine in the newborn rat and locomotor responses to drugs in infancy: no support for the dopamine depletion model of minimal brain dysfunction.

Authors:  B A Pappas; J V Gallivan; T Dugas; M Saari; R Ings
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530
  9 in total

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