Literature DB >> 942800

Selective brain dopamine depletion in developing rats: an experimental model of minimal brain dysfunction.

B A Shaywitz, R D Yager, J H Klopper.   

Abstract

Administration of 6-hydroxydopamine to neonatal rats produces a rapid and profound depletion of brain dopamine. Total activity of treated animals is significantly greater than that of controls between 12 and 22 days of age, but then declines, an activity pattern similar to that seen in affected children. This suggests a functional deficiency of brain dopamine in the pathogenesis of minimal brain dysfunction.

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Year:  1976        PMID： 942800     DOI： 10.1126/science.942800

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  59 in total

Review 1.  The effects of prenatal alcohol exposure on behavior: rodent and primate studies.

Authors:  Mary L Schneider; Colleen F Moore; Miriam M Adkins
Journal:  Neuropsychol Rev       Date:  2011-04-19       Impact factor: 7.444

2.  Plasticity within striatal direct pathway neurons after neonatal dopamine depletion is mediated through a novel functional coupling of serotonin 5-HT2 receptors to the ERK 1/2 map kinase pathway.

Authors:  Pierre Brown; Charles R Gerfen
Journal:  J Comp Neurol       Date:  2006-09-20       Impact factor: 3.215

3.  Altered Corticostriatal Connectivity and Exploration/Exploitation Imbalance Emerge as Intermediate Phenotypes for a Neonatal Dopamine Dysfunction.

Authors:  Barbara Y Braz; Gregorio L Galiñanes; Irene R E Taravini; Juan E Belforte; M Gustavo Murer
Journal:  Neuropsychopharmacology       Date:  2015-04-15       Impact factor: 7.853

4.  Differential effects of prenatal exposure to phenobarbital on the behaviour and neurochemistry of CBA and C57BL/6J mice.

Authors:  S K Sedowofia; J Innes; A Peter; E Alleva; A Manning; R M Clayton
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530

Review 5.  Animal models to guide clinical drug development in ADHD: lost in translation?

Authors:  Jeffery R Wickens; Brian I Hyland; Gail Tripp
Journal:  Br J Pharmacol       Date:  2011-10       Impact factor: 8.739

Review 6.  Pharmacological models of ADHD.

Authors:  R M Kostrzewa; J P Kostrzewa; R A Kostrzewa; P Nowak; R Brus
Journal:  J Neural Transm (Vienna)       Date:  2007-11-12       Impact factor: 3.575

7.  Dopaminergic but not noradrenergic mediation of hyperactivity and performance deficits in the developing rat pup.

Authors:  B A Shaywitz; M H Teicher; D J Cohen; G M Anderson; J G Young; P Levitt
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

Review 8.  Dopamine receptor supersensitivity: development, mechanisms, presentation, and clinical applicability.

Authors:  Richard M Kostrzewa; John P Kostrzewa; Russell W Brown; Przemyslaw Nowak; Ryszard Brus
Journal:  Neurotox Res       Date:  2008-10       Impact factor: 3.911

9.  Unilateral neonatal intracerebroventricular 6-hydroxydopamine administration in rats: I. Effects on spontaneous and drug-induced rotational behaviour and on postmortem monoamine levels.

Authors:  J Luthman; M Herrera-Marschitz; E Lindqvist
Journal:  Psychopharmacology (Berl)       Date:  1994-12       Impact factor: 4.530

10.  Effects of neonatal treatment with 5,7-dihydroxytryptamine or 6-hydroxydopamine on the ontogenetic development of the audiogenic immobility reaction in the rat.

Authors:  E Hard; S Ahlenius; J Engel
Journal:  Psychopharmacology (Berl)       Date:  1983       Impact factor: 4.530
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