Literature DB >> 9876539

The use of beta-cyclodextrin as a pelletization agent in the extrusion/spheronization process.

A Gazzaniga1, M E Sangalli, G Bruni, L Zema, C Vecchio, F Giordano.   

Abstract

The use of beta-cyclodextrin for the preparation of pellets by the extrusion/spheronization process is described for different formulations and processing conditions. Sieve analysis and friability tests were performed to assess the physical and technological characteristics of pellets. Satisfactory products were obtained with beta-cyclodextrin contents up to 90% by weight.

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Year:  1998        PMID： 9876539     DOI： 10.3109/03639049809088533

Source DB:  PubMed          Journal:  Drug Dev Ind Pharm        ISSN： 0363-9045            Impact factor:   3.225


  4 in total

1.  Direct pelletization in a rotary processor controlled by torque measurements. II: effects of changes in the content of microcrystalline cellulose.

Authors:  J Kristensen; T Schaefer; P Kleinebudde
Journal:  AAPS PharmSci       Date:  2000

Review 2.  Cyclodextrins in drug delivery: an updated review.

Authors:  Rajeswari Challa; Alka Ahuja; Javed Ali; R K Khar
Journal:  AAPS PharmSciTech       Date:  2005-10-14       Impact factor: 3.246

3.  Functionality of cross-linked polyvinylpyrrolidone as a spheronization aid: a promising alternative to microcrystalline cellulose.

Authors:  Celine V Liew; Li Gu; Josephine L P Soh; Paul W S Heng
Journal:  Pharm Res       Date:  2005-08-03       Impact factor: 4.200

4.  The use of beta-cyclodextrin in the manufacturing of disintegrating pellets with improved dissolution performances.

Authors:  Lucia Zema; Luca Palugan; Alessandra Maroni; Anastasia Foppoli; Maria Edvige Sangalli; Andrea Gazzaniga
Journal:  AAPS PharmSciTech       Date:  2008-06-04       Impact factor: 3.246
  4 in total

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