Literature DB >> 987520

Metabolism of 2,4-3H-14alpha-methyl-5alpha-ergost-8-enol and 2,4-3H-5alpha-ergosta-8,14-dienol in Ochromonas malhamensis.

J H Adler, G W Patterson.   

Abstract

Tritium-labeled 14alpha-methyl-5alpha-ergost-8-enol and 5alpha-ergosta-8,14-dienol were converted to brassicasterol and poriferasterol in Ochromonas malhamensis. This indicates that the organism can rearrange these sterol structures so that they contain the naturally occurring 5(6) double bond, and suggests that O. malhamensis is able to introduce a 24(28) double bond into a nine-carbon saturated side chain which is alkylated to produce a C-29 sterol.

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Year:  1976        PMID： 987520     DOI： 10.1007/bf02532878

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  10 in total

1.  Separation of sterol acetates by column and thin-layer argentation chromatography.

Authors:  H E Vroman; C F Cohen
Journal:  J Lipid Res       Date:  1967-03       Impact factor: 5.922

2.  AY-9944 inhibition of sterol biosynthesis in Chlorella emersonii.

Authors:  L G Dickson; G W Patterson
Journal:  Lipids       Date:  1973-08       Impact factor: 1.880

3.  The sterols of Ochromonas danica and Ochromonas malhamensis.

Authors:  M C Gershengorn; A R Smith; G Goulston; L J Goad; T W Goodwin; T H Haines
Journal:  Biochemistry       Date:  1968-05       Impact factor: 3.162

4.  Studies on phytosterol biosynthesis: metabolism of 24,25-dihydrolanosterol and cholesterol in Ochromonas malhamensis.

Authors:  G H Beastall; H H Rees; T W Goodwin
Journal:  Biochem J       Date:  1972-06       Impact factor: 3.857

5.  Evidence for the biological conversion of delta 8,14 sterol dienes into cholesterol.

Authors:  L Canonica; A Fiecchi; M G Kienle; A Scala; G Galli; E G Paoletti; R Paoletti
Journal:  J Am Chem Soc       Date:  1968-11-06       Impact factor: 15.419

6.  Studies on the enzymatic conversion of 5 alpha-cholesta-8, 14-dien-3 beta-ol to cholesterol.

Authors:  B N Lutsky; G J Schroepfer
Journal:  J Biol Chem       Date:  1970-12-10       Impact factor: 5.157

7.  The role of a cholesta-8,14-dien-3-beta-ol system in cholesterol biosynthesis.

Authors:  M Akhtar; I A Watkinson; A D Rahimtula; D C Wilton; K A Munday
Journal:  Biochem J       Date:  1969-03       Impact factor: 3.857

8.  4,4-dimethyl-5-alpha-cholesta-8,14-dien-3-beta-ol. A new precursor of cholesterol in mammalian tissues.

Authors:  A Fiecchi; L Canonica; A Scala; F Cattabeni; E G Paoletti; R Paoletti
Journal:  Life Sci       Date:  1969-06-15       Impact factor: 5.037

9.  Triparanol Inhibition of Sterol Biosynthesis in Chlorella ellipsoidea.

Authors:  J T Chan; G W Patterson
Journal:  Plant Physiol       Date:  1973-09       Impact factor: 8.340

10.  Metabolism of 2,4 -3H - 14alpha-methyl -5alpha-ergost - 8-enol and 2,4- 3H- 5 alpha- ergosta-8, 14-dienol in chlorella ellipsoidea.

Authors:  L B Tsai; G W Patterson; C F Cohen
Journal:  Lipids       Date:  1974-12       Impact factor: 1.880
  10 in total
  1 in total

1.  Cooccurrence of C-24 alkylated Δ(7)- and Δ(5)-Sterols in the leaves ofBeta vulgarisin the leaves ofBeta vulgaris.

Authors:  J H Adler; T A Salt
Journal:  Lipids       Date:  1983-03       Impact factor: 1.880
  1 in total

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