Literature DB >> 9873666

Triple helix stabilization properties of oligonucleotides containing 8-amino-2'-deoxyguanosine.

R Güimil García1, A Bachi, R Eritja, F J Luque, M Orozco.   

Abstract

Analysis of the Hoogsteen base pairs of guanine and 8-aminoguanine with cytosine in the gase phase shows a strong stabilization of the 8-aminoguanine.cytosine base pair due to the formation of an extra H-bond. Melting profiles of oligonucleotides carrying 8-amino-2'-deoxyguanosine confirm the triple helix stabilization properties of 8-aminoguanine.

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Year:  1998        PMID: 9873666     DOI: 10.1016/s0960-894x(98)00537-x

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  3 in total

1.  DNA-triplex stabilizing properties of 8-aminoguanine.

Authors:  R Soliva; R Güimil García; J R Blas; R Eritja; J L Asensio; C González; F J Luque; M Orozco
Journal:  Nucleic Acids Res       Date:  2000-11-15       Impact factor: 16.971

2.  The effect of amino groups on the stability of DNA duplexes and triplexes based on purines derived from inosine.

Authors:  E Cubero; R Güimil-García; F J Luque; R Eritja; M Orozco
Journal:  Nucleic Acids Res       Date:  2001-06-15       Impact factor: 16.971

3.  Monitoring denaturation behaviour and comparative stability of DNA triple helices using oligonucleotide-gold nanoparticle conjugates.

Authors:  Deirdre Murphy; Ramon Eritja; Gareth Redmond
Journal:  Nucleic Acids Res       Date:  2004-04-23       Impact factor: 16.971

  3 in total

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