| Literature DB >> 9873597 |
J C Medina1, B Shan, H Beckmann, R P Farrell, D L Clark, R M Learned, D Roche, A Li, V Baichwal, C Case, P A Baeuerle, T Rosen, J C Jaen.
Abstract
A novel series of pentafluorobenzenesulfonamides has been shown to inhibit the growth of a variety of human tumor cell lines. Among the cell types against which these agents were evaluated were the multidrug resistant (MDR) cell lines MCF-7/ADR and P388/ADR. The cytotoxic activity of members of this series of compounds was not affected by the multidrug resistant pump in MCF-7/ADR or P388/ADR cells.Entities:
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Year: 1998 PMID： 9873597 DOI： 10.1016/s0960-894x(98)00477-6
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823