Literature DB >> 9873570

Naphthoquinone analogs as inactivators of cdc25 phosphatase.

S W Ham1, J Park, S J Lee, W Kim, K Kang, K H Choi.   

Abstract

cdc25A and cdc25B were significantly overexpressed in certain types of cancers, and they represent potential therapeutic targets for anticancer drug. In this study, naphthoquinone analogs as cdc25A phosphatase inactivators were investigated.

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Year:  1998        PMID: 9873570     DOI: 10.1016/s0960-894x(98)00411-9

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  6 in total

Review 1.  Cdc25 as a potential target of anticancer agents.

Authors:  J W Eckstein
Journal:  Invest New Drugs       Date:  2000-05       Impact factor: 3.850

2.  Development of antiproliferative phenylmaleimides that activate the unfolded protein response.

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Journal:  Bioorg Med Chem       Date:  2010-04-24       Impact factor: 3.641

3.  Identification of chemical inhibitors to human tissue transglutaminase by screening existing drug libraries.

Authors:  Thung-S Lai; Yusha Liu; Tim Tucker; Kurt R Daniel; David C Sane; Eric Toone; James R Burke; Warren J Strittmatter; Charles S Greenberg
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Review 4.  Covalent inhibition of protein tyrosine phosphatases.

Authors:  Kasi Viswanatharaju Ruddraraju; Zhong-Yin Zhang
Journal:  Mol Biosyst       Date:  2017-06-27

5.  Screening the active constituents of Chinese medicinal herbs as potent inhibitors of Cdc25 tyrosine phosphatase, an activator of the mitosis-inducing p34cdc2 kinase.

Authors:  Hua Yang; Shu Zheng; Laurent Meijer; Shi-min Li; Sophie Leclerc; Lin-lin Yu; Jin-quan Cheng; Su-zhan Zhang
Journal:  J Zhejiang Univ Sci B       Date:  2005-07       Impact factor: 3.066

Review 6.  A Comprehensive Overview of the Developments of Cdc25 Phosphatase Inhibitors.

Authors:  Ahmed Bakr Abdelwahab; Eslam Reda El-Sawy; Atef G Hanna; Denyse Bagrel; Gilbert Kirsch
Journal:  Molecules       Date:  2022-04-07       Impact factor: 4.927

  6 in total

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