| Literature DB >> 9873510 |
N Sakurai1, M Sano, F Hirayama, T Kuroda, S Uemori, A Moriguchi, K Yamamoto, Y Ikeda, T Kawakita.
Abstract
A series of the titled compounds was synthesized and tested for anti-Helicobacter pylori activities. We discovered Y-34867 having the most potent activity against Helicobacter pylori among the quinolones tested along with high photostability. Furthermore, Y-34867 showed an excellent therapeutic effect in the experimental Helicobacter pylori infected Mongolian gerbil model.Entities:
Mesh:
Substances:
Year: 1998 PMID: 9873510 DOI: 10.1016/s0960-894x(98)00390-4
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823