| Literature DB >> 9873461 |
Z Sui1, J Guan, D J Hlasta, M J Macielag, B D Foleno, R M Goldschmidt, M J Loeloff, G C Webb, J F Barrett.
Abstract
A series of diaryltriazole analogs was discovered to inhibit bacterial two-component regulatory systems in our primary assays, KinA/Spo0F and NRII/NRI. They also showed inhibitory activity in whole cell mechanism-based assays, and they possessed potent activities against several strains of Gram-positive pathogenic bacteria in the standard MIC broth assay.Entities:
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Year: 1998 PMID： 9873461 DOI： 10.1016/s0960-894x(98)00325-4
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823