Literature DB >> 9871635

Novel antiproliferative falcarindiol furanocoumarin ethers from the root of Angelica japonica.

K Furumi1, T Fujioka, H Fujii, H Okabe, Y Nakano, H Matsunaga, M Katano, M Mori, K Mihashi.   

Abstract

Four novel antiproliferative furanocoumarin ethers of falcarindiol, named japoangelols A (8.5), B (7.2), C (7.4), and D (8.4), were isolated from the root of Angelica japonica together with panaxynol (0.3), falcarindiol (3.2), (9Z)-1,9-heptadecadiene-4,6-diyne-3,8,11-triol (2.2), and 8-acetoxyfalcarinol (3.2). Structures were established from the spectroscopic evidence, and the inhibitory activities (ED50, microgram/ml, shown in the parentheses) were evaluated using the MTT assay.

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Year:  1998        PMID： 9871635     DOI： 10.1016/s0960-894x(97)10193-7

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  8 in total

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  8 in total

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