| Literature DB >> 9871630 |
Y P Auberson1, S Bischoff, R Moretti, M Schmutz, S J Veenstra.
Abstract
A series of 5-aminomethylquinoxaline-2,3-diones have been identified as potent and selective AMPA antagonists. Some of these compounds are also active at the glycine-binding site of the NMDA receptors. A number of these novel, water-soluble quinoxaline-2,3-dione derivatives display protective effects in the electroshock-induced convulsion model in mice.Entities:
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Year: 1998 PMID： 9871630 DOI： 10.1016/s0960-894x(97)10186-x
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823