| Literature DB >> 986559 |
G H Lyman, H D Preisler, D Papahadjopoulos.
Abstract
DMSO and other cryoprotective agents produce a pronounced increase on the phase transition temperature of phospholipid membranes, indicating an increased stability. The effects of DMSO and other cryoprotective agents, divalent cations, and local anaesthetics on the transition temperature of phospholipid membranes seem to correlate with their effects on the differentiation of Friend leukaemic cells in vitro. These studies suggest that the induction of differentiation by cryoprotective agents may be the result of the interaction of these agents with cell membranes.Entities:
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Year: 1976 PMID： 986559 DOI： 10.1038/262360a0
Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962