Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Supersensitivity of cortical neurones of the rat to acetylcholine and L-glutamate following chronic morphine treatment.

Literature DB >> 986007

Supersensitivity of cortical neurones of the rat to acetylcholine and L-glutamate following chronic morphine treatment.

Abstract

the effect of microelectrophoretically applied L-glutamate and acetylcholine on discharge activity of cortical neurones was studied in naive and in morphine-tolerant/dependent rats. The thresholds for increase in discharge activity elicited by these 2 putative neurotransmitters were 3 times lower in the tolerant/dependent rats than in the naive rats, indicating the development of supersensitivity.

Entities: Chemical Species

Mesh：

Substances：

Year: 1976 PMID： 986007 DOI： 10.1007/bf00498877

Source DB: PubMed Journal: Naunyn Schmiedebergs Arch Pharmacol ISSN： 0028-1298 Impact factor: 3.000

17 in total

1. Interaction between morphine and putative excitatory neurotransmitters in cortical neurons in naive and tolerant rats.

Authors: M Satoh; W Zieglgänsberger; A Herz
Journal: Life Sci Date: 1975-07-01 Impact factor: 5.037

2. Morphine induced calcium depletion in discrete regions of rat brain.

Authors: H L Cardenas; D H Ross
Journal: J Neurochem Date: 1975-03 Impact factor: 5.372

3. Opiate agonist-antagonist interaction at cortical neurones of naive and tolerant/dependent rats.

Authors: M Satoh; W Zieglgänsberger; W Fries; A Herz
Journal: Brain Res Date: 1974-12-27 Impact factor: 3.252

4. Action of 5-hydroxytryptamine on electrical activity of Auerbach's plexus in the ileum of the morphine dependent guinea pig.

Authors: I Takayanagi; T Sato; K Takagi
Journal: Eur J Pharmacol Date: 1974-07 Impact factor: 4.432

Supersensitivity of cortical neurones of the rat to acetylcholine and L-glutamate following chronic morphine treatment.

1. Interaction between morphine and putative excitatory neurotransmitters in cortical neurons in naive and tolerant rats.

2. Morphine induced calcium depletion in discrete regions of rat brain.

3. Opiate agonist-antagonist interaction at cortical neurones of naive and tolerant/dependent rats.

4. Action of 5-hydroxytryptamine on electrical activity of Auerbach's plexus in the ileum of the morphine dependent guinea pig.

5. Nonspecific supersensitivity of the guinea-pig vas deferens produced by decentralization and reserpine treatment.

6. XVII. Pharmacological denervation supersensitivity in the central nervous system: a theory of physical dependence.

7. Responses of the isolated ileum of the morphine-tolerant guinea pig.

Review 8. Amino acid transmitters in the mammalian central nervous system.

9. A possible role for tissue calcium in reserpine supersensitivity.

10. Morphine and ethanol: selective depletion of regional brain calcium.

1. Sensitivity of morphine-tolerant rats to muscarinic and dopaminergic agonists: relation to tolerance or withdrawal.

2. Naloxone-precipitated withdrawal reveals sensitization to neurotransmitters in morphine tolerant/dependent rats.

3. Glutamate sensitivity and distribution of receptors along normal and denervated locust muscle fibres.

Review 4. Glutamatergic substrates of drug addiction and alcoholism.