Literature DB >> 4420821

Morphine and ethanol: selective depletion of regional brain calcium.

D H Ross, M A Medina, H L Cardenas.   

Abstract

Administration of morphine or ethanol to rats produces a decrease in regional brain calcium in vivo. This effect is selectively antagonized by the stereospecific narcotic antagonist naloxone. Reserpine and the dopamine-acetaldehyde conjugate salsolinol also produce a depletion of regional brain calcium, but only the salsolinol depletion is antagonized by naloxone. Experiments with naloxone provide evidence for two calcium-sensitive pools in the central nervous system.

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Year:  1974        PMID： 4420821     DOI： 10.1126/science.186.4158.63

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  18 in total

1.  Reserpine-induced changes in the uptake and distribution of radiolabelled calcium and magnesium in the brain and pituitary gland of the rat.?

Authors:  I Sabbot; E Rovner; A Costin
Journal:  Experientia       Date:  1975-07-15

2.  Morphine suppression of ethanol withdrawal in mice.

Authors:  K Blum; J E Wallace; H A Schwerter; J D Eubanks
Journal:  Experientia       Date:  1976-01-15

3.  Calcium channel involvement in magnetic field inhibition of morphine-induced analgesia.

Authors:  M Kavaliers; K P Ossenkopp
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1987-09       Impact factor: 3.000

4.  The effects of ethanol on embryonic actin: a possible role in teratogenesis.

Authors:  J A Hassler; D J Moran
Journal:  Experientia       Date:  1986-05-15

5.  Role of alcohol in clinical nephrology.

Authors:  A Heidland; W H Hörl; R M Schaefer; M Teschner; J Weipert; E Heidbreder
Journal:  Klin Wochenschr       Date:  1985-09-16

6.  Calcium depletion of synaptosomes after morphine treatment.

Authors:  H L Cardenas; D H Ross
Journal:  Br J Pharmacol       Date:  1976-08       Impact factor: 8.739

7.  The mechanism and overcoming of resistance in ACNU-resistant sublines of C6 and 9L rat glioma.

Authors:  T Yoshida; K Shimizu; Y Ushio; T Hayakawa; H Mogami; Y Sakamoto
Journal:  J Neurooncol       Date:  1987       Impact factor: 4.130

8.  Regional calcium levels in rat and mouse brain: automated fluorimetric assay and effects of centrally acting drugs.

Authors:  J Korf; F H Zoethout; F Postema
Journal:  Psychopharmacology (Berl)       Date:  1983       Impact factor: 4.530

9.  Mitochondrial calcium sequestration in cortical and hippocampal neurons after prolonged ischemia of the cat brain.

Authors:  K A Hossmann; B Grosse Ophoff; R Schmidt-Kastner; U Oschlies
Journal:  Acta Neuropathol       Date:  1985       Impact factor: 17.088

10.  Inhibition of Ca2+-induced noradrenaline release from central noradrenergic neurons by morphine.

Authors:  M Göthert; E Wehking
Journal:  Experientia       Date:  1980-02-15
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