| Literature DB >> 985421 |
Abstract
A single administration of 2-allyl-2-isopropylacetamide, a porphyrinogenic drug, enhanced the 32P-labelling of nucleoplasmic as well as cytoplasmic poly(A)-containing RNA in rat liver. The synthesis of total microsomal RNA is only marginally increased under these conditions. The drug enhances the labelling of a variety of cytoplasmic poly(A)-containing RNA species, and this effect is counteracted by the simultaneous administration of haemin. 2-Allyl-2-isopropylacetamide also enhanced the release of RNA from the nucleus to the cytoplasm.Entities:
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Year: 1976 PMID: 985421 PMCID: PMC1163956 DOI: 10.1042/bj1580169
Source DB: PubMed Journal: Biochem J ISSN: 0264-6021 Impact factor: 3.857