Literature DB >> 1156384

Effect of allylisopropylacetamide on Nuclear Ribonucleic Acid synthesis in rat liver.

M K Sardana, M R Satyanarayana Rao, G Padmanaban.   

Abstract

The porphyrogenic drug allylisopropylacetamide, a potent inducer of delta-aminolaevulinate synthetase, specifically increases nucleoplasmic RNA synthesis in rat liver. The drug-mediated increase in nucleoplasmic RNA synthesis is blocked by cycloheximide and haemin, which also inhibit the enzyme induction.

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Year:  1975        PMID： 1156384      PMCID： PMC1165390          DOI： 10.1042/bj1470185

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  11 in total

1.  Induction of -aminolevulinic acid synthetase in chick embryo liver cells in cluture.

Authors:  S Sassa; S Granick
Journal:  Proc Natl Acad Sci U S A       Date:  1970-10       Impact factor: 11.205

Review 2.  Disturbances of liver porphyrin metabolism caused by drugs.

Authors:  F de Matteis
Journal:  Pharmacol Rev       Date:  1967-12       Impact factor: 25.468

3.  Studies on SDS-phenol methods for extraction of rat liver nuclear RNA. I. Purity, recovery, and specific radioactivity of pulse labeled nuclear RNA obtained by SDS-phenol extraction under various conditions.

Authors:  S Abe; T Fujisawa; M Satake; K Ogata
Journal:  J Biochem       Date:  1972-09       Impact factor: 3.387

4.  Loss of haem in rat liver caused by the porphyrogenic agent 2-allyl-2-isopropylacetamide.

Authors:  F De Matteis
Journal:  Biochem J       Date:  1971-10       Impact factor: 3.857

5.  Methylation of ribosomal RNA precursor and tRNA in rat liver.

Authors:  M Muramatsu; T Fujisawa
Journal:  Biochim Biophys Acta       Date:  1968-05-21

6.  The induction in vitro of the synthesis of delta-aminolevulinic acid synthetase in chemical porphyria: a response to certain drugs, sex hormones, and foreign chemicals.

Authors:  S Granick
Journal:  J Biol Chem       Date:  1966-03-25       Impact factor: 5.157

7.  Delta-aminolevulinic acid synthetase. II. Induction in rat liver.

Authors:  H S Marver; A Collins; D P Tschudy; M Rechcigl
Journal:  J Biol Chem       Date:  1966-10-10       Impact factor: 5.157

8.  Nuclei from rat liver: isolation method that combines purity with high yield.

Authors:  G Blobel; V R Potter
Journal:  Science       Date:  1966-12-30       Impact factor: 47.728

9.  A model for the regulation of delta-aminolaevulinate synthetase induction in rat liver.

Authors:  G Padmanaban; M R Rao; K Malathi
Journal:  Biochem J       Date:  1973-08       Impact factor: 3.857

10.  Steroid control of porphyrin and heme biosynthesis: a new biological function of steroid hormone metabolites.

Authors:  S Granick; A Kappas
Journal:  Proc Natl Acad Sci U S A       Date:  1967-05       Impact factor: 11.205
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  2 in total

1.  Effect of 2-allyl-2-isopropylacetamide on poly(adenylic acid)-containing ribonucleic acid.

Authors:  M K Sardana; G Padmanaban
Journal:  Biochem J       Date:  1976-08-15       Impact factor: 3.857

2.  A comparative study of the early effects of phenobarbital and 3-methylcholanthrene on the synthesis and transport of ribonucleic acid in rat liver.

Authors:  A Kumar; M R Rao; G Padmanaban
Journal:  Biochem J       Date:  1980-01-15       Impact factor: 3.857
  2 in total

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