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Literature DB >> 984808

Concentration of cefamandole in serum interstitial fluid, bile, and urine.

N G Waterman, H U Eickenberg, L Scharfenberger.

Abstract

Cefamandole readily diffuses from the serum into soft tissue interstitial fluid. The rate of diffusion differs little from that of cephalothin. The concentrations of antibiotic were greater in bile and urine during the entire period of study than is necessary to kill susceptible pathogenic bacteria present in these fluids.

Entities: Chemical

Mesh：

Substances：

Year: 1976 PMID： 984808 PMCID： PMC429822 DOI： 10.1128/AAC.10.4.733

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

12 in total

1. Concentration of antibiotics in renal interstitial fluid: an experimental model.

Authors: H U Eickenberg; N G Waterman; L Scharfenberger
Journal: Urol Res Date: 1975-12-30

2. Renal interstitial fluid, urine, and serum antibiotic concentration.

Authors: H U Eickenberg; N G Waterman; L Scharfenberger
Journal: Surg Forum Date: 1975

3. Protein binding and concentrations of cephaloridine and cefazolin in serum and interstitial fluid of dogs.

Authors: N G Waterman; M J Raff; L Scharfenberger; P A Barnwell
Journal: J Infect Dis Date: 1976-06 Impact factor: 5.226

4. Rate of binding of antibiotics to canine serum protein.

Authors: N Waterman; L Scharfenberger; M J Raff
Journal: Antimicrob Agents Chemother Date: 1974-03 Impact factor: 5.191

5. Concentration of antibacterial agents in interstitial tissue fluid.

Authors: G D Chisholm; P M Waterworth; J S Calnan; L P Garrod
Journal: Br Med J Date: 1973-03-10

6. Interstitial fluid and serum antibiotic concentrations.

Authors: N G Waterman; L B Kastan
Journal: Arch Surg Date: 1972-08

7. Rapid microassay for circulating nephrotoxic antibiotics.

Authors: L D Sabath; J I Casey; P A Ruch; L L Stumpf; M Finland
Journal: Antimicrob Agents Chemother (Bethesda) Date: 1970

8. Cefamandole, a cephalosporin antibiotic with an unusually wide spectrum of activity.

Authors: H C Neu
Journal: Antimicrob Agents Chemother Date: 1974-08 Impact factor: 5.191

9. In vitro studies of cefamandole.

Authors: G P Bodey; S Weaver
Journal: Antimicrob Agents Chemother Date: 1976-03 Impact factor: 5.191

10. Antibacterial activity of cefamandole, a new cephalosporin antibiotic, compared with that of cephaloridine, cephalothin, and cephalexin.

Authors: S Eykyn; C Jenkins; A King; I Phillips
Journal: Antimicrob Agents Chemother Date: 1973-06 Impact factor: 5.191

7 in total

Concentration of cefamandole in serum interstitial fluid, bile, and urine.

1. Concentration of antibiotics in renal interstitial fluid: an experimental model.

2. Renal interstitial fluid, urine, and serum antibiotic concentration.

3. Protein binding and concentrations of cephaloridine and cefazolin in serum and interstitial fluid of dogs.

4. Rate of binding of antibiotics to canine serum protein.

5. Concentration of antibacterial agents in interstitial tissue fluid.

6. Interstitial fluid and serum antibiotic concentrations.

7. Rapid microassay for circulating nephrotoxic antibiotics.

8. Cefamandole, a cephalosporin antibiotic with an unusually wide spectrum of activity.

9. In vitro studies of cefamandole.

10. Antibacterial activity of cefamandole, a new cephalosporin antibiotic, compared with that of cephaloridine, cephalothin, and cephalexin.

1. Pharmacokinetics of cefamandole using a HPLC assay.

2. Newer antibiotics.

3. Pharmacokinetics of cefamandole in osseous tissue.

4. Ascitic fluid cephalosporin concentrations: influence of protein binding and serum pharmacokinetics.

5. Cephalosporins: recent developments.

6. Biliary and pancreatic excretion of cefamandole.

Review 7. The cephalosporins: activity and clinical use.