| Literature DB >> 9834156 |
J Qian-Cutrone1, J M Kolb, K McBrien, S Huang, D Gustavson, S E Lowe, S P Manly.
Abstract
Two new naphthacenequinone glycosides, quanolirones I (1) and II (2) were isolated, together with the known compound galtamycin from the fermentation broth of Streptomyces sp. WC76535. The structures 1 and 2 were established by analysis of their spectroscopic data and by comparison of their data to those of galtamycin. Compounds 1, 2, and galtamycin showed inhibitory activity against HCMV protease with IC50 values of 14, 35, and 52 microM, respectively.Entities:
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Year: 1998 PMID： 9834156 DOI： 10.1021/np980234k
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050