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Literature DB >> 9834005

Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats.

W L Chiou¹, A Barve.

Abstract

Entities: Species

Mesh：

Year: 1998 PMID： 9834005 DOI： 10.1023/a:1011981317451

Source DB: PubMed Journal: Pharm Res ISSN： 0724-8741 Impact factor: 4.200

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16 in total

1. Human intestinal permeability of piroxicam, propranolol, phenylalanine, and PEG 400 determined by jejunal perfusion.

Authors: N Takamatsu; L S Welage; N M Idkaidek; D Y Liu; P I Lee; Y Hayashi; J K Rhie; H Lennernäs; J L Barnett; V P Shah; L Lesko; G L Amidon
Journal: Pharm Res Date: 1997-09 Impact factor: 4.200

Review 2. Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond.

Authors: P Artursson; R T Borchardt
Journal: Pharm Res Date: 1997-12 Impact factor: 4.200

3. In vitro permeability through caco-2 cells is not quantitatively predictive of in vivo absorption for peptide-like drugs absorbed via the dipeptide transporter system.

Authors: S Chong; S A Dando; K M Soucek; R A Morrison
Journal: Pharm Res Date: 1996-01 Impact factor: 4.200

4. Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells.

Authors: P Artursson; J Karlsson
Journal: Biochem Biophys Res Commun Date: 1991-03-29 Impact factor: 3.575

5. The validation of the intestinal permeability approach to predict oral fraction of dose absorbed in humans and rats.

Authors: W L Chiou
Journal: Biopharm Drug Dispos Date: 1995-01 Impact factor: 1.627

6. Chronic dog intestinal loop model for studying drug absorption as exemplified by beta-adrenoreceptor blocking agents, atenolol and propranolol.

Authors: D C Taylor; R Grundy; B Loveday
Journal: J Pharm Sci Date: 1981-05 Impact factor: 3.534

7. A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability.

Authors: G L Amidon; H Lennernäs; V P Shah; J R Crison
Journal: Pharm Res Date: 1995-03 Impact factor: 4.200

8. Evaluation of potential causes for the incomplete bioavailability of furosemide: gastric first-pass metabolism.

Authors: M G Lee; W L Chiou
Journal: J Pharmacokinet Biopharm Date: 1983-12

9. The phenomenon and cause of the dose-dependent oral absorption of chlorothiazide in rats: extrapolation to human data based on the body surface area concept.

Authors: F H Hsu; T Prueksaritanont; M G Lee; W L Chiou
Journal: J Pharmacokinet Biopharm Date: 1987-08

Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats.

1. Human intestinal permeability of piroxicam, propranolol, phenylalanine, and PEG 400 determined by jejunal perfusion.

Review 2. Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond.

3. In vitro permeability through caco-2 cells is not quantitatively predictive of in vivo absorption for peptide-like drugs absorbed via the dipeptide transporter system.

4. Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells.

5. The validation of the intestinal permeability approach to predict oral fraction of dose absorbed in humans and rats.

6. Chronic dog intestinal loop model for studying drug absorption as exemplified by beta-adrenoreceptor blocking agents, atenolol and propranolol.

7. A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability.

8. Evaluation of potential causes for the incomplete bioavailability of furosemide: gastric first-pass metabolism.

9. The phenomenon and cause of the dose-dependent oral absorption of chlorothiazide in rats: extrapolation to human data based on the body surface area concept.

10. Measurements of the jejunal unstirred layer in normal subjects and patients with celiac disease.

1. Poor and unusually prolonged oral absorption of amphotericin B in rats.

2. Rate-limited steps of human oral absorption and QSAR studies.

3. Quantitative biopharmaceutics classification system: the central role of dose/solubility ratio.

Review 4. Why is it challenging to predict intestinal drug absorption and oral bioavailability in human using rat model.

5. PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange.

Review 6. Prediction of hepatic clearance in human from in vitro data for successful drug development.

7. Fasting increases tobramycin oral absorption in mice.

Review 8. Towards quantitative prediction of oral drug absorption.

9. Practical anticipation of human efficacious doses and pharmacokinetics using in vitro and preclinical in vivo data.

10. Interspecies modeling and prediction of human exenatide pharmacokinetics.