Literature DB >> 8668660

In vitro permeability through caco-2 cells is not quantitatively predictive of in vivo absorption for peptide-like drugs absorbed via the dipeptide transporter system.

S Chong1, S A Dando, K M Soucek, R A Morrison.   

Abstract

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Year:  1996        PMID： 8668660     DOI： 10.1023/a:1016045820933

Source DB:  PubMed          Journal:  Pharm Res        ISSN： 0724-8741            Impact factor:   4.200


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  14 in total

1.  Disposition of pravastatin sodium, a tissue-selective HMG-CoA reductase inhibitor, in healthy subjects.

Authors:  S M Singhvi; H Y Pan; R A Morrison; D A Willard
Journal:  Br J Clin Pharmacol       Date:  1990-02       Impact factor: 4.335

2.  Antimicrobial activity and human pharmacology of amoxicillin.

Authors:  H C Neu
Journal:  J Infect Dis       Date:  1974-06       Impact factor: 5.226

3.  Cephalexin: pharmacologic evaluation following oral and parenteral administration.

Authors:  P Nicholas; B R Meyers; S Z Hirschman
Journal:  J Clin Pharmacol       Date:  1973 Nov-Dec       Impact factor: 3.126

4.  Uptake of the cephalosporin, cephalexin, by a dipeptide transport carrier in the human intestinal cell line, Caco-2.

Authors:  A H Dantzig; L Bergin
Journal:  Biochim Biophys Acta       Date:  1990-09-07

5.  Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells.

Authors:  P Artursson; J Karlsson
Journal:  Biochem Biophys Res Commun       Date:  1991-03-29       Impact factor: 3.575

6.  Association of intestinal peptide transport with a protein related to the cadherin superfamily.

Authors:  A H Dantzig; J A Hoskins; L B Tabas; S Bright; R L Shepard; I L Jenkins; D C Duckworth; J R Sportsman; D Mackensen; P R Rosteck
Journal:  Science       Date:  1994-04-15       Impact factor: 47.728

7.  Disposition of 14C-guanabenz in patients with essential hypertension.

Authors:  R H Meacham; M Emmett; A A Kyriakopoulos; S T Chiang; H W Ruelius; B R Walker; R G Narins; M Goldberg
Journal:  Clin Pharmacol Ther       Date:  1980-01       Impact factor: 6.875

8.  Transepithelial transport of oral cephalosporins by monolayers of intestinal epithelial cell line Caco-2: specific transport systems in apical and basolateral membranes.

Authors:  K Inui; M Yamamoto; H Saito
Journal:  J Pharmacol Exp Ther       Date:  1992-04       Impact factor: 4.030

9.  Metabolic studies in patients with nadolol: oral and intravenous administration.

Authors:  J Dreyfuss; L J Brannick; R A Vukovich; J M Shaw; D A Willard
Journal:  J Clin Pharmacol       Date:  1977 May-Jun       Impact factor: 3.126

Review 10.  Lisinopril: a new angiotensin-converting enzyme inhibitor.

Authors:  G M Armayor; L M Lopez
Journal:  Drug Intell Clin Pharm       Date:  1988-05
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  19 in total

1.  Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs.

Authors:  Duxin Sun; Hans Lennernas; Lynda S Welage; Jeffery L Barnett; Christopher P Landowski; David Foster; David Fleisher; Kyung-Dall Lee; Gordon L Amidon
Journal:  Pharm Res       Date:  2002-10       Impact factor: 4.200

2.  Transport of pregabalin in rat intestine and Caco-2 monolayers.

Authors:  N Jezyk; C Li; B H Stewart; X Wu; H N Bockbrader; D Fleisher
Journal:  Pharm Res       Date:  1999-04       Impact factor: 4.200

3.  Transepithelial transport of bepridil in the human intestinal cell line, Caco-2, using a "dynamic model".

Authors:  F Mathieu; M J Galmier; A Nicolay; J F Pognat; C Lartigue
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2003 Apr-Jun       Impact factor: 2.441

Review 4.  Current industrial practices of assessing permeability and P-glycoprotein interaction.

Authors:  Praveen V Balimane; Yong-Hae Han; Saeho Chong
Journal:  AAPS J       Date:  2006-01-13       Impact factor: 4.009

Review 5.  Towards quantitative prediction of oral drug absorption.

Authors:  Jennifer B Dressman; Kirstin Thelen; Ekarat Jantratid
Journal:  Clin Pharmacokinet       Date:  2008       Impact factor: 6.447

6.  Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats.

Authors:  W L Chiou; A Barve
Journal:  Pharm Res       Date:  1998-11       Impact factor: 4.200

7.  Predicting the extent of metabolism using in vitro permeability rate measurements and in silico permeability rate predictions.

Authors:  Chelsea M Hosey; Leslie Z Benet
Journal:  Mol Pharm       Date:  2015-04-23       Impact factor: 4.939

8.  Drug discovery and regulatory considerations for improving in silico and in vitro predictions that use Caco-2 as a surrogate for human intestinal permeability measurements.

Authors:  Caroline A Larregieu; Leslie Z Benet
Journal:  AAPS J       Date:  2013-01-24       Impact factor: 4.009

9.  Suitability of enalapril as a probe of the dipeptide transporter system: in vitro and in vivo studies.

Authors:  R A Morrison; S Chong; A M Marino; M A Wasserman; P Timmins; V A Moore; W J Irwin
Journal:  Pharm Res       Date:  1996-07       Impact factor: 4.200

10.  The use of low molecular weight protamine chemical chimera to enhance monomeric insulin intestinal absorption.

Authors:  Huining He; Jianyong Sheng; Allan E David; Young Min Kwon; Jian Zhang; Yongzhuo Huang; Jianxin Wang; Victor C Yang
Journal:  Biomaterials       Date:  2013-07-14       Impact factor: 12.479
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