Literature DB >> 9825278

Fatal flecainide intoxication.

E Brazil1, G G Bodiwala, D C Bouch.   

Abstract

Flecainide acetate is a potent class 1C antiarrhythmic agent used mainly for the treatment of supraventricular arrhythmias. Acute overdose of this drug is rare but frequently fatal. The clinical course of a patient that ingested a large quantity of flecainide as a suicide attempt is described and current therapeutic strategies discussed.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9825278      PMCID： PMC1343219          DOI： 10.1136/emj.15.6.423

Source DB:  PubMed          Journal:  J Accid Emerg Med        ISSN： 1351-0622


  11 in total

1.  Relative role of alkalosis and sodium ions in reversal of class I antiarrhythmic drug-induced sodium channel blockade by sodium bicarbonate.

Authors:  E Bou-Abboud; S Nattel
Journal:  Circulation       Date:  1996-10-15       Impact factor: 29.690

2.  [Hemoperfusion in flecainide poisoning].

Authors:  R Wurzberger; E Witter; H Avenhaus; H Hennemann; J U Becker
Journal:  Klin Wochenschr       Date:  1986-05-02

3.  Emergency use of cardiopulmonary bypass.

Authors:  P A Overlie
Journal:  J Interv Cardiol       Date:  1995-06       Impact factor: 2.279

4.  Flecainide overdose: is cardiopulmonary support the treatment?

Authors:  R K Yasui; T F Culclasure; D Kaufman; C R Freed
Journal:  Ann Emerg Med       Date:  1997-05       Impact factor: 5.721

5.  Fatal flecainide intoxication.

Authors:  C Rogers; D T Anderson; J K Ribe; L Sathyavagiswaran
Journal:  J Anal Toxicol       Date:  1993 Nov-Dec       Impact factor: 3.367

6.  Suppression of resistant ventricular arrhythmias by twice daily dosing with flecainide.

Authors:  H J Duff; D M Roden; R J Maffucci; B S Vesper; G J Conard; S B Higgins; J A Oates; R F Smith; R L Woosley
Journal:  Am J Cardiol       Date:  1981-12       Impact factor: 2.778

7.  Persistent electrocardiographic changes after flecainide overdose.

Authors:  J Greig; B M Groden
Journal:  Br J Clin Pract       Date:  1995 Jul-Aug

8.  Reversal of flecainide-induced ventricular arrhythmia by hypertonic sodium bicarbonate in dogs.

Authors:  D M Salerno; M M Murakami; R B Johnston; D E Keyler; P R Pentel
Journal:  Am J Emerg Med       Date:  1995-05       Impact factor: 2.469

9.  Primary and secondary detoxification in severe flecainide intoxication.

Authors:  D Götz; S Pohle; D Barckow
Journal:  Intensive Care Med       Date:  1991       Impact factor: 17.440

10.  Desensitization and down-regulation of neurotensin receptors in murine neuroblastoma clone N1E-115 by [D-Lys8] neurotensin(8-13).

Authors:  E Donato di Paola; B Cusack; M Yamada; E Richelson
Journal:  J Pharmacol Exp Ther       Date:  1993-01       Impact factor: 4.030
View more
  3 in total

Review 1.  Pharmacologic management of arrhythmias.

Authors:  Leila Ganjehei; Ali Massumi; Alireza Nazeri; Mehdi Razavi
Journal:  Tex Heart Inst J       Date:  2011

2.  [Fatal flecainide intoxication in a 17-year-old girl].

Authors:  M Dokter; G Talarico; S Armbrust; E Below; B Bockholdt
Journal:  Anaesthesist       Date:  2018-03-28       Impact factor: 1.041

3.  ECG diagnosis: flecainide toxicity.

Authors:  Joel T Levis
Journal:  Perm J       Date:  2012
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.